Chen H - Search Results

1

Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation.

Leong SR, DeForge L, Presta L, Gonzalez T, Fan A, Reichert M, Chuntharapai A, Kim KJ, Tumas DB, Lee WP, Gribling P, Snedecor B, Chen H, Hsei V, Schoenhoff M, Hale V, Deveney J, Koumenis I, Shahrokh Z, McKay P, Galan W, Wagner B, Narindray D, Hébert C, Zapata G. Leong SR, et al. Among authors: chen h. Cytokine. 2001 Nov 7;16(3):106-19. doi: 10.1006/cyto.2001.0936. Cytokine. 2001. PMID: 11741351

2

Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders.

Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, Krummen L, Winkler M, Ferrara N. Presta LG, et al. Among authors: chen h. Cancer Res. 1997 Oct 15;57(20):4593-9. Cancer Res. 1997. PMID: 9377574

3

The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade.

Davis-Smyth T, Chen H, Park J, Presta LG, Ferrara N. Davis-Smyth T, et al. Among authors: chen h. EMBO J. 1996 Sep 16;15(18):4919-27. EMBO J. 1996. PMID: 8890165 Free PMC article.

4

Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans.

Mordenti J, Thomsen K, Licko V, Chen H, Meng YG, Ferrara N. Mordenti J, et al. Among authors: chen h. Toxicol Pathol. 1999 Jan-Feb;27(1):14-21. doi: 10.1177/019262339902700104. Toxicol Pathol. 1999. PMID: 10367667

5

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis.

Keyt BA, Nguyen HV, Berleau LT, Duarte CM, Park J, Chen H, Ferrara N. Keyt BA, et al. Among authors: chen h. J Biol Chem. 1996 Mar 8;271(10):5638-46. doi: 10.1074/jbc.271.10.5638. J Biol Chem. 1996. PMID: 8621427 Free article.

6

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration.

Gille H, Kowalski J, Yu L, Chen H, Pisabarro MT, Davis-Smyth T, Ferrara N. Gille H, et al. Among authors: chen h. EMBO J. 2000 Aug 1;19(15):4064-73. doi: 10.1093/emboj/19.15.4064. EMBO J. 2000. PMID: 10921887 Free PMC article.

7

The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency.

Keyt BA, Berleau LT, Nguyen HV, Chen H, Heinsohn H, Vandlen R, Ferrara N. Keyt BA, et al. Among authors: chen h. J Biol Chem. 1996 Mar 29;271(13):7788-95. doi: 10.1074/jbc.271.13.7788. J Biol Chem. 1996. PMID: 8631822 Free article.

8

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene.

Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW. Ferrara N, et al. Among authors: chen h. Nature. 1996 Apr 4;380(6573):439-42. doi: 10.1038/380439a0. Nature. 1996. PMID: 8602242 Free article.

9

Vascular endothelial growth factor is essential for corpus luteum angiogenesis.

Ferrara N, Chen H, Davis-Smyth T, Gerber HP, Nguyen TN, Peers D, Chisholm V, Hillan KJ, Schwall RH. Ferrara N, et al. Among authors: chen h. Nat Med. 1998 Mar;4(3):336-40. doi: 10.1038/nm0398-336. Nat Med. 1998. PMID: 9500609

10

Molecular module for glucose production influences sex pheromone synthesis in Bactrocera dorsalis.

Li X, Wang Z, Chen J, Teng H, Yang X, Ye L, Jiang Y, Chen H, Cheng D, Lu Y. Li X, et al. Among authors: chen h. Cell Rep. 2024 Nov 30;43(12):115030. doi: 10.1016/j.celrep.2024.115030. Online ahead of print. Cell Rep. 2024. PMID: 39616614

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