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SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence.
Gioia U, Tavella S, Martínez-Orellana P, Cicio G, Colliva A, Ceccon M, Cabrini M, Henriques AC, Fumagalli V, Paldino A, Presot E, Rajasekharan S, Iacomino N, Pisati F, Matti V, Sepe S, Conte MI, Barozzi S, Lavagnino Z, Carletti T, Volpe MC, Cavalcante P, Iannacone M, Rampazzo C, Bussani R, Tripodo C, Zacchigna S, Marcello A, d'Adda di Fagagna F. Gioia U, et al. Among authors: sepe s. Nat Cell Biol. 2023 Apr;25(4):550-564. doi: 10.1038/s41556-023-01096-x. Epub 2023 Mar 9. Nat Cell Biol. 2023. PMID: 36894671 Free PMC article.
Preliminary report in treatment of proximal humeral fracture with closed reduction and DOS external fixation System: a multicentric study.
Scaravilli G, Mercurio J, Grazioli A, Gioia C, D'Arienzo A, Toro G, Galvano N, Monteleone G, Battaglini G, Di Santo F, Sepe S, Pagliuca S, Cesarano E, Mastrobuono G, Italiano M, D'Arienzo M, Maniscalco P, Ciatti C, Di Maggio B. Scaravilli G, et al. Among authors: sepe s. Acta Biomed. 2022 May 11;93(2):e2021494. doi: 10.23750/abm.v93i2.11924. Acta Biomed. 2022. PMID: 35546021 Free PMC article.
DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering.
Milanese C, Bombardieri CR, Sepe S, Barnhoorn S, Payán-Goméz C, Caruso D, Audano M, Pedretti S, Vermeij WP, Brandt RMC, Gyenis A, Wamelink MM, de Wit AS, Janssens RC, Leen R, van Kuilenburg ABP, Mitro N, Hoeijmakers JHJ, Mastroberardino PG. Milanese C, et al. Among authors: sepe s. Nat Commun. 2019 Oct 25;10(1):4887. doi: 10.1038/s41467-019-12640-5. Nat Commun. 2019. PMID: 31653834 Free PMC article.
Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease.
Sepe S, Milanese C, Gabriels S, Derks KW, Payan-Gomez C, van IJcken WF, Rijksen YM, Nigg AL, Moreno S, Cerri S, Blandini F, Hoeijmakers JH, Mastroberardino PG. Sepe S, et al. Cell Rep. 2016 May 31;15(9):1866-75. doi: 10.1016/j.celrep.2016.04.071. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210754 Free PMC article.
60 results