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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
Pozeg ZI, Michelakis ED, McMurtry MS, Thébaud B, Wu XC, Dyck JR, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer SL. Pozeg ZI, et al. Among authors: moudgil r. Circulation. 2003 Apr 22;107(15):2037-44. doi: 10.1161/01.CIR.0000062688.76508.B3. Epub 2003 Apr 14. Circulation. 2003. PMID: 12695303
Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
Thébaud B, Michelakis ED, Wu XC, Moudgil R, Kuzyk M, Dyck JR, Harry G, Hashimoto K, Haromy A, Rebeyka I, Archer SL. Thébaud B, et al. Among authors: moudgil r. Circulation. 2004 Sep 14;110(11):1372-9. doi: 10.1161/01.CIR.0000141292.28616.65. Epub 2004 Sep 7. Circulation. 2004. PMID: 15353504
Hypoxic pulmonary vasoconstriction.
Moudgil R, Michelakis ED, Archer SL. Moudgil R, et al. J Appl Physiol (1985). 2005 Jan;98(1):390-403. doi: 10.1152/japplphysiol.00733.2004. J Appl Physiol (1985). 2005. PMID: 15591309 Free article. Review.
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thébaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL. Bonnet S, et al. Among authors: moudgil r. Circulation. 2006 Jun 6;113(22):2630-41. doi: 10.1161/CIRCULATIONAHA.105.609008. Epub 2006 May 30. Circulation. 2006. PMID: 16735674
84 results