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Page 1
Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M, Noh G, Goodman J, Hagger GN, Tran J, Tippin TK, Wang X, Lusis AJ, Hsueh WA, Law RE, Collins JL, Willson TM, Tontonoz P. Joseph SB, et al. Among authors: collins jl, collins ar. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7604-9. doi: 10.1073/pnas.112059299. Proc Natl Acad Sci U S A. 2002. PMID: 12032330 Free PMC article.
Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue.
Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, Castrillo A, Wilpitz DC, Mangelsdorf DJ, Collins JL, Saez E, Tontonoz P. Laffitte BA, et al. Among authors: collins jl. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5419-24. doi: 10.1073/pnas.0830671100. Epub 2003 Apr 15. Proc Natl Acad Sci U S A. 2003. PMID: 12697904 Free PMC article.
Autoregulation of the human liver X receptor alpha promoter.
Laffitte BA, Joseph SB, Walczak R, Pei L, Wilpitz DC, Collins JL, Tontonoz P. Laffitte BA, et al. Among authors: collins jl. Mol Cell Biol. 2001 Nov;21(22):7558-68. doi: 10.1128/MCB.21.22.7558-7568.2001. Mol Cell Biol. 2001. PMID: 11604492 Free PMC article.
Sterol regulatory element-binding protein-1c is responsible for cholesterol regulation of ileal bile acid-binding protein gene in vivo. Possible involvement of liver-X-receptor.
Zaghini I, Landrier JF, Grober J, Krief S, Jones SA, Monnot MC, Lefrere I, Watson MA, Collins JL, Fujii H, Besnard P. Zaghini I, et al. Among authors: collins jl. J Biol Chem. 2002 Jan 11;277(2):1324-31. doi: 10.1074/jbc.M106375200. Epub 2001 Oct 29. J Biol Chem. 2002. PMID: 11684682 Free article.
Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages.
Whitney KD, Watson MA, Goodwin B, Galardi CM, Maglich JM, Wilson JG, Willson TM, Collins JL, Kliewer SA. Whitney KD, et al. Among authors: collins jl. J Biol Chem. 2001 Nov 23;276(47):43509-15. doi: 10.1074/jbc.M106155200. Epub 2001 Aug 23. J Biol Chem. 2001. PMID: 11546778 Free article.
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.
Jaye MC, Krawiec JA, Campobasso N, Smallwood A, Qiu C, Lu Q, Kerrigan JJ, De Los Frailes Alvaro M, Laffitte B, Liu WS, Marino JP Jr, Meyer CR, Nichols JA, Parks DJ, Perez P, Sarov-Blat L, Seepersaud SD, Steplewski KM, Thompson SK, Wang P, Watson MA, Webb CL, Haigh D, Caravella JA, Macphee CH, Willson TM, Collins JL. Jaye MC, et al. Among authors: collins jl. J Med Chem. 2005 Aug 25;48(17):5419-22. doi: 10.1021/jm050532w. J Med Chem. 2005. PMID: 16107141
281 results