Ireland LM - Search Results

1

Preclinical pharmacology of fiduxosin, a novel alpha(1)-adrenoceptor antagonist with uroselective properties.

Hancock AA, Buckner SA, Brune ME, Esbenshade TA, Ireland LM, Katwala S, Milicic I, Meyer MD, Kerwin JF Jr, Williams M. Hancock AA, et al. Among authors: ireland lm. J Pharmacol Exp Ther. 2002 Feb;300(2):478-86. doi: 10.1124/jpet.300.2.478. J Pharmacol Exp Ther. 2002. PMID: 11805207

2

Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenoceptor agonist.

Altenbach RJ, Khilevich A, Kolasa T, Rohde JJ, Bhatia PA, Patel MV, Searle XB, Yang F, Bunnelle WH, Tietje K, Bayburt EK, Carroll WA, Meyer MD, Henry R, Buckner SA, Kuk J, Daza AV, Milicic IV, Cain JC, Kang CH, Ireland LM, Carr TL, Miller TR, Hancock AA, Nakane M, Esbenshade TA, Brune ME, O'Neill AB, Gauvin DM, Katwala SP, Holladay MW, Brioni JD, Sullivan JP. Altenbach RJ, et al. Among authors: ireland lm. J Med Chem. 2004 Jun 3;47(12):3220-35. doi: 10.1021/jm030551a. J Med Chem. 2004. PMID: 15163201

3

Actions of terazosin and its enantiomers at subtypes of alpha 1- and alpha 2-adrenoceptors in vitro.

Hancock AA, Buckner SA, Ireland LM, Knepper SM, Kerwin JF Jr. Hancock AA, et al. Among authors: ireland lm. J Recept Signal Transduct Res. 1995 Sep-Dec;15(7-8):863-85. doi: 10.3109/10799899509049862. J Recept Signal Transduct Res. 1995. PMID: 8673721

4

Effects of selective and nonselective alpha-1-adrenoceptor antagonists on intraurethral and arterial pressures in intact conscious dogs.

Brune ME, Katwala SP, Milicic I, Buckner SA, Ireland LM, Kerwin JF Jr, Hancock AA. Brune ME, et al. Among authors: ireland lm. Pharmacology. 1996 Dec;53(6):356-68. doi: 10.1159/000139451. Pharmacology. 1996. PMID: 9032800

5

Actions of A-131701, a novel, selective antagonist for alpha-1A compared with alpha-1B adrenoceptors on intraurethral and blood pressure responses in conscious dogs and a pharmacodynamic assessment of in vivo prostatic selectivity.

Hancock AA, Brune ME, Witte DG, Marsh KC, Katwala S, Milicic I, Ireland LM, Crowell D, Meyer MD, Kerwin JF Jr. Hancock AA, et al. Among authors: ireland lm. J Pharmacol Exp Ther. 1998 May;285(2):628-42. J Pharmacol Exp Ther. 1998. PMID: 9580607

6

[3H]R-terazosin binds selectively to alpha1-adrenoceptors over alpha2-adrenoceptors - comparison with racemic [3H]terazosin and [3H]prazosin.

Ireland LM, Cain JC, Rotert G, Thomas S, Shoghi S, Hancock AA, Kerwin JF Jr. Ireland LM, et al. Eur J Pharmacol. 1997 May 26;327(1):79-86. doi: 10.1016/s0014-2999(97)89681-1. Eur J Pharmacol. 1997. PMID: 9185839

7

Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1.

Faghih R, Dwight W, Gentles R, Phelan K, Esbenshade TA, Ireland L, Miller TR, Kang CH, Fox GB, Gopalakrishnan SM, Hancock AA, Bennani YL. Faghih R, et al. Bioorg Med Chem Lett. 2002 Aug 5;12(15):2031-4. doi: 10.1016/s0960-894x(02)00309-8. Bioorg Med Chem Lett. 2002. PMID: 12113835

8

Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 2: binding preference for D-amino acids motifs.

Faghih R, Dwight W, Black L, Liu H, Gentles R, Phelan K, Esbenshade TA, Ireland L, Miller TR, Kang CH, Krueger KM, Fox GB, Hancock AA, Bennani YL. Faghih R, et al. Bioorg Med Chem Lett. 2002 Aug 5;12(15):2035-7. doi: 10.1016/s0960-894x(02)00310-4. Bioorg Med Chem Lett. 2002. PMID: 12113836

9

Synthesis and evaluation of potent pyrrolidine H(3) antagonists.

Vasudevan A, Conner SE, Gentles RG, Faghih R, Liu H, Dwight W, Ireland L, Kang CH, Esbenshade TA, Bennani YL, Hancock AA. Vasudevan A, et al. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3055-8. doi: 10.1016/s0960-894x(02)00685-6. Bioorg Med Chem Lett. 2002. PMID: 12372500

10

Differential effects of 2,4-dithiobiuret on the synthesis and release of acetylcholine and dopamine from rat pheochromocytoma (PC12) cells.

Ireland LM, Yan CH, Nelson LM, Atchison WD. Ireland LM, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1453-62. J Pharmacol Exp Ther. 1995. PMID: 8531116

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