IJzerman AP - Search Results

1

General T-cell receptor antagonists to immunomodulate HLA-A2-restricted minor histocompatibility antigen HA-1-specific T-cell responses.

den Haan JM, Mutis T, Blokland E, IJzerman AP, Goulmy E. den Haan JM, et al. Among authors: ijzerman ap. Blood. 2002 Feb 1;99(3):985-92. doi: 10.1182/blood.v99.3.985. Blood. 2002. PMID: 11807003 Free article.

2

Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor.

de Ligt RA, van der Klein PA, von Frijtag Drabbe Künzel JK, Lorenzen A, Ait El Maate F, Fujikawa S, van Westhoven R, van den Hoven T, Brussee J, IJzerman AP. de Ligt RA, et al. Among authors: ijzerman ap. Bioorg Med Chem. 2004 Jan 2;12(1):139-49. doi: 10.1016/j.bmc.2003.10.023. Bioorg Med Chem. 2004. PMID: 14697779

3

Small molecule antagonists for chemokine CCR3 receptors.

Willems LI, Ijzerman AP. Willems LI, et al. Among authors: ijzerman ap. Med Res Rev. 2010 Sep;30(5):778-817. doi: 10.1002/med.20181. Med Res Rev. 2010. PMID: 19967721 Review.

4

Medicinal chemistry of adenosine A1 receptor ligands.

Soudijn W, van Wijngaarden I, IJzerman AP. Soudijn W, et al. Among authors: ijzerman ap. Curr Top Med Chem. 2003;3(4):355-67. doi: 10.2174/1568026033392165. Curr Top Med Chem. 2003. PMID: 12570755 Review.

5

Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Klaasse E, de Ligt RA, Roerink SF, Lorenzen A, Milligan G, Leurs R, IJzerman AP. Klaasse E, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2004 Sep 19;499(1-2):91-8. doi: 10.1016/j.ejphar.2004.07.108. Eur J Pharmacol. 2004. PMID: 15363955

6

Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene core.

Bonger KM, van den Berg RJ, Knijnenburg AD, Heitman LH, Ijzerman AP, Oosterom J, Timmers CM, Overkleeft HS, van der Marel GA. Bonger KM, et al. Among authors: ijzerman ap. Bioorg Med Chem. 2008 Apr 1;16(7):3744-58. doi: 10.1016/j.bmc.2008.01.054. Epub 2008 Feb 2. Bioorg Med Chem. 2008. PMID: 18282756

7

Allosteric modulators affect the internalization of human adenosine A1 receptors.

Klaasse EC, van den Hout G, Roerink SF, de Grip WJ, Ijzerman AP, Beukers MW. Klaasse EC, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2005 Oct 17;522(1-3):1-8. doi: 10.1016/j.ejphar.2005.08.052. Epub 2005 Oct 7. Eur J Pharmacol. 2005. PMID: 16214128

8

A "locked-on," constitutively active mutant of the adenosine A1 receptor.

de Ligt RA, Rivkees SA, Lorenzen A, Leurs R, IJzerman AP. de Ligt RA, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2005 Mar 7;510(1-2):1-8. doi: 10.1016/j.ejphar.2005.01.007. Eur J Pharmacol. 2005. PMID: 15740718

9

Stochastic multidimensional hypercubes and inverse agonism.

Milligan G, Ijzerman AP. Milligan G, et al. Among authors: ijzerman ap. Trends Pharmacol Sci. 2000 Oct;21(10):362-3. doi: 10.1016/s0165-6147(00)01540-6. Trends Pharmacol Sci. 2000. PMID: 11203388 No abstract available.

10

Allosteric modulation of G protein-coupled receptors.

Ijzerman A, Kourounakis A, van der Klein P. Ijzerman A, et al. Farmaco. 2001 Jan-Feb;56(1-2):67-70. doi: 10.1016/s0014-827x(01)01015-1. Farmaco. 2001. PMID: 11347969

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