Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV.
Richard E, Alam SM, Arredondo-Vega FX, Patel DD, Hershfield MS.
Richard E, et al.
J Biol Chem. 2002 May 31;277(22):19720-6. doi: 10.1074/jbc.M111901200. Epub 2002 Mar 18.
J Biol Chem. 2002.
PMID: 11901152
Free article.
Among the 5 non-conserved residues within this segment, Arg-142 in human and Gln-142 in mouse ADA largely determined the capacity for stable binding to CD26 (Richard, E., Arredondo-Vega, F. X., Santisteban, I., Kelly, S. J., Patel, D. D., and Hershfield, M. ...
Among the 5 non-conserved residues within this segment, Arg-142 in human and Gln-142 in mouse ADA largely determined the capacity for stable …