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3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.
Bioorg Med Chem. 2002 Jun;10(6):2031-49. doi: 10.1016/s0968-0896(02)00016-0.
Bioorg Med Chem. 2002.
PMID: 11937363
15-Fluoro prostaglandin FP agonists: a new class of topical ocular hypotensives.
Klimko P, Hellberg M, McLaughlin M, Sharif N, Severns B, Williams G, Haggard K, Liao J.
Klimko P, et al.
Bioorg Med Chem. 2004 Jul 1;12(13):3451-69. doi: 10.1016/j.bmc.2004.04.034.
Bioorg Med Chem. 2004.
PMID: 15186831
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In vivo optimization of 2,3-diaminopyrazine Rho Kinase inhibitors for the treatment of glaucoma.
Chen HH, Namil A, Severns B, Ward J, Kelly C, Drace C, McLaughlin MA, Yacoub S, Li B, Patil R, Sharif N, Hellberg MR, Rusinko A, Pang IH, Combrink KD.
Chen HH, et al.
Bioorg Med Chem Lett. 2014 Apr 15;24(8):1875-9. doi: 10.1016/j.bmcl.2014.03.017. Epub 2014 Mar 19.
Bioorg Med Chem Lett. 2014.
PMID: 24684843
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Ocular Hypotensive Response in Nonhuman Primates of (8R)-1-[(2S)-2-Aminopropyl]-8,9-dihydro-7H-pyrano[2,3-g]indazol-8-ol a Selective 5-HT2 Receptor Agonist.
May JA, Sharif NA, McLaughlin MA, Chen HH, Severns BS, Kelly CR, Holt WF, Young R, Glennon RA, Hellberg MR, Dean TR.
May JA, et al. Among authors: severns bs.
J Med Chem. 2015 Nov 25;58(22):8818-33. doi: 10.1021/acs.jmedchem.5b00857. Epub 2015 Nov 9.
J Med Chem. 2015.
PMID: 26551970
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