Williams GW - Search Results

1

3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.

Hellberg MR, Conrow RE, Sharif NA, McLaughlin MA, Bishop JE, Crider JY, Dean WD, DeWolf KA, Pierce DR, Sallee VL, Selliah RD, Severns BS, Sproull SJ, Williams GW, Zinke PW, Klimko PG. Hellberg MR, et al. Among authors: williams gw. Bioorg Med Chem. 2002 Jun;10(6):2031-49. doi: 10.1016/s0968-0896(02)00016-0. Bioorg Med Chem. 2002. PMID: 11937363

2

15-Fluoro prostaglandin FP agonists: a new class of topical ocular hypotensives.

Klimko P, Hellberg M, McLaughlin M, Sharif N, Severns B, Williams G, Haggard K, Liao J. Klimko P, et al. Bioorg Med Chem. 2004 Jul 1;12(13):3451-69. doi: 10.1016/j.bmc.2004.04.034. Bioorg Med Chem. 2004. PMID: 15186831

3

Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity.

Feng Z, Mohapatra S, Klimko PG, Hellberg MR, May JA, Kelly C, Williams G, McLaughlin MA, Sharif NA. Feng Z, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):2998-3002. doi: 10.1016/j.bmcl.2007.03.073. Epub 2007 Mar 25. Bioorg Med Chem Lett. 2007. PMID: 17419053

4

AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey.

Selliah RD, Hellberg MR, Sharif NA, McLaughlin MA, Williams GW, Scott DA, Earnest D, Haggard KS, Dean WD, Delgado P, Gaines MS, Conrow RE, Klimko PG. Selliah RD, et al. Among authors: williams gw. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4525-8. doi: 10.1016/j.bmcl.2004.06.037. Bioorg Med Chem Lett. 2004. PMID: 15357985

5

Molecular pharmacology of the DP/EP2 class prostaglandin AL-6598 and quantitative autoradiographic visualization of DP and EP2 receptor sites in human eyes.

Sharif NA, Williams GW, Crider JY, Xu SX, Davis TL. Sharif NA, et al. Among authors: williams gw. J Ocul Pharmacol Ther. 2004 Dec;20(6):489-508. doi: 10.1089/jop.2004.20.489. J Ocul Pharmacol Ther. 2004. PMID: 15684809

6

Preclinical pharmacology of AL-12182, a new ocular hypotensive 11-oxa prostaglandin analog.

Sharif NA, McLaughlin MA, Kelly CR, Xu S, Crider JY, Williams GW, Parker JL. Sharif NA, et al. Among authors: williams gw. J Ocul Pharmacol Ther. 2006 Oct;22(5):291-309. doi: 10.1089/jop.2006.22.291. J Ocul Pharmacol Ther. 2006. PMID: 17076623

7

Discovery of 13-oxa prostaglandin analogs as antiglaucoma agents: synthesis and biological activity.

Feng Z, Hellberg MR, Sharif NA, McLaughlin MA, Williams GW, Scott D, Wallace T. Feng Z, et al. Among authors: williams gw. Bioorg Med Chem. 2009 Jan 15;17(2):576-84. doi: 10.1016/j.bmc.2008.11.070. Epub 2008 Dec 6. Bioorg Med Chem. 2009. PMID: 19101156

8

Bimatoprost and its free acid are prostaglandin FP receptor agonists.

Sharif NA, Williams GW, Kelly CR. Sharif NA, et al. Among authors: williams gw. Eur J Pharmacol. 2001 Dec 7;432(2-3):211-3. doi: 10.1016/s0014-2999(01)01486-8. Eur J Pharmacol. 2001. PMID: 11740958

9

Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in cultured cells.

Sharif NA, Kelly CR, Crider JY, Williams GW, Xu SX. Sharif NA, et al. Among authors: williams gw. J Ocul Pharmacol Ther. 2003 Dec;19(6):501-15. doi: 10.1089/108076803322660422. J Ocul Pharmacol Ther. 2003. PMID: 14733708

10

Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost, unoprostone, and other analogs via endogenous mouse, rat, and cloned human FP prostaglandin receptors.

Kelly CR, Williams GW, Sharif NA. Kelly CR, et al. Among authors: williams gw. J Pharmacol Exp Ther. 2003 Jan;304(1):238-45. doi: 10.1124/jpet.102.042556. J Pharmacol Exp Ther. 2003. PMID: 12490597

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