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Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.
Vasseur F, Helbecque N, Dina C, Lobbens S, Delannoy V, Gaget S, Boutin P, Vaxillaire M, Leprêtre F, Dupont S, Hara K, Clément K, Bihain B, Kadowaki T, Froguel P. Vasseur F, et al. Among authors: clement k. Hum Mol Genet. 2002 Oct 1;11(21):2607-14. doi: 10.1093/hmg/11.21.2607. Hum Mol Genet. 2002. PMID: 12354786
Genetics of obesity.
Clement K, Boutin P, Froguel P. Clement K, et al. Am J Pharmacogenomics. 2002;2(3):177-87. doi: 10.2165/00129785-200202030-00003. Am J Pharmacogenomics. 2002. PMID: 12383024 Review.
GAD2 on chromosome 10p12 is a candidate gene for human obesity.
Boutin P, Dina C, Vasseur F, Dubois S, Corset L, Séron K, Bekris L, Cabellon J, Neve B, Vasseur-Delannoy V, Chikri M, Charles MA, Clement K, Lernmark A, Froguel P. Boutin P, et al. Among authors: clement k. PLoS Biol. 2003 Dec;1(3):E68. doi: 10.1371/journal.pbio.0000068. Epub 2003 Nov 3. PLoS Biol. 2003. PMID: 14691540 Free PMC article.
703 results