Siderovski DP - Search Results

1

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.

Snyder JT, Worthylake DK, Rossman KL, Betts L, Pruitt WM, Siderovski DP, Der CJ, Sondek J. Snyder JT, et al. Among authors: siderovski dp. Nat Struct Biol. 2002 Jun;9(6):468-75. doi: 10.1038/nsb796. Nat Struct Biol. 2002. PMID: 12006984

2

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

Rossman KL, Worthylake DK, Snyder JT, Siderovski DP, Campbell SL, Sondek J. Rossman KL, et al. Among authors: siderovski dp. EMBO J. 2002 Mar 15;21(6):1315-26. doi: 10.1093/emboj/21.6.1315. EMBO J. 2002. PMID: 11889037 Free PMC article.

3

Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.

Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Kimple RJ, et al. Among authors: siderovski dp. Nature. 2002 Apr 25;416(6883):878-81. doi: 10.1038/416878a. Nature. 2002. PMID: 11976690

4

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

Booden MA, Siderovski DP, Der CJ. Booden MA, et al. Among authors: siderovski dp. Mol Cell Biol. 2002 Jun;22(12):4053-61. doi: 10.1128/MCB.22.12.4053-4061.2002. Mol Cell Biol. 2002. PMID: 12024019 Free PMC article.

5

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism.

Lambert JM, Lambert QT, Reuther GW, Malliri A, Siderovski DP, Sondek J, Collard JG, Der CJ. Lambert JM, et al. Among authors: siderovski dp. Nat Cell Biol. 2002 Aug;4(8):621-5. doi: 10.1038/ncb833. Nat Cell Biol. 2002. PMID: 12134164

6

Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling.

Pruitt WM, Karnoub AE, Rakauskas AC, Guipponi M, Antonarakis SE, Kurakin A, Kay BK, Sondek J, Siderovski DP, Der CJ. Pruitt WM, et al. Among authors: siderovski dp. Biochim Biophys Acta. 2003 Apr 7;1640(1):61-8. doi: 10.1016/s0167-4889(03)00002-8. Biochim Biophys Acta. 2003. PMID: 12676355 Free article.

7

Crystal structure of the multifunctional Gbeta5-RGS9 complex.

Cheever ML, Snyder JT, Gershburg S, Siderovski DP, Harden TK, Sondek J. Cheever ML, et al. Among authors: siderovski dp. Nat Struct Mol Biol. 2008 Feb;15(2):155-62. doi: 10.1038/nsmb.1377. Epub 2008 Jan 20. Nat Struct Mol Biol. 2008. PMID: 18204463 Free PMC article.

8

Quantitative analysis of the effect of phosphoinositide interactions on the function of Dbl family proteins.

Snyder JT, Rossman KL, Baumeister MA, Pruitt WM, Siderovski DP, Der CJ, Lemmon MA, Sondek J. Snyder JT, et al. Among authors: siderovski dp. J Biol Chem. 2001 Dec 7;276(49):45868-75. doi: 10.1074/jbc.M106731200. Epub 2001 Sep 27. J Biol Chem. 2001. PMID: 11577097 Free article.

9

Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases.

Rojas RJ, Kimple RJ, Rossman KL, Siderovski DP, Sondek J. Rojas RJ, et al. Among authors: siderovski dp. Comb Chem High Throughput Screen. 2003 Jun;6(4):409-18. doi: 10.2174/138620703106298509. Comb Chem High Throughput Screen. 2003. PMID: 12769685 Review.

10

Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange.

Johnston CA, Willard FS, Jezyk MR, Fredericks Z, Bodor ET, Jones MB, Blaesius R, Watts VJ, Harden TK, Sondek J, Ramer JK, Siderovski DP. Johnston CA, et al. Among authors: siderovski dp. Structure. 2005 Jul;13(7):1069-80. doi: 10.1016/j.str.2005.04.007. Structure. 2005. PMID: 16004878 Free PMC article.

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