Kim HS - Search Results

1

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

Kim SA, Marshall MA, Melman N, Kim HS, Müller CE, Linden J, Jacobson KA. Kim SA, et al. Among authors: kim hs. J Med Chem. 2002 May 23;45(11):2131-8. doi: 10.1021/jm0104318. J Med Chem. 2002. PMID: 12014951 Free PMC article.

2

Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.

Kim HS, Ravi RG, Marquez VE, Maddileti S, Wihlborg AK, Erlinge D, Malmsjö M, Boyer JL, Harden TK, Jacobson KA. Kim HS, et al. J Med Chem. 2002 Jan 3;45(1):208-18. doi: 10.1021/jm010369e. J Med Chem. 2002. PMID: 11754592 Free PMC article.

3

Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.

Ravi RG, Kim HS, Servos J, Zimmermann H, Lee K, Maddileti S, Boyer JL, Harden TK, Jacobson KA. Ravi RG, et al. Among authors: kim hs. J Med Chem. 2002 May 9;45(10):2090-100. doi: 10.1021/jm010538v. J Med Chem. 2002. PMID: 11985476 Free PMC article.

4

Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation.

Xu B, Stephens A, Kirschenheuter G, Greslin AF, Cheng X, Sennelo J, Cattaneo M, Zighetti ML, Chen A, Kim SA, Kim HS, Bischofberger N, Cook G, Jacobson KA. Xu B, et al. Among authors: kim hs, kim sa. J Med Chem. 2002 Dec 19;45(26):5694-709. doi: 10.1021/jm020173u. J Med Chem. 2002. PMID: 12477353 Free PMC article.

5

2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.

Kim HS, Ohno M, Xu B, Kim HO, Choi Y, Ji XD, Maddileti S, Marquez VE, Harden TK, Jacobson KA. Kim HS, et al. Among authors: kim ho. J Med Chem. 2003 Nov 6;46(23):4974-87. doi: 10.1021/jm030127+. J Med Chem. 2003. PMID: 14584948 Free PMC article.

6

Nucleotide analogues containing 2-oxa-bicyclo[2.2.1]heptane and l-alpha-threofuranosyl ring systems: interactions with P2Y receptors.

Ohno M, Costanzi S, Kim HS, Kempeneers V, Vastmans K, Herdewijn P, Maddileti S, Gao ZG, Harden TK, Jacobson KA. Ohno M, et al. Among authors: kim hs. Bioorg Med Chem. 2004 Nov 1;12(21):5619-30. doi: 10.1016/j.bmc.2004.07.067. Bioorg Med Chem. 2004. PMID: 15465340 Free PMC article.

7

Synthesis of a novel conformationally locked carbocyclic nucleoside ring system.

Kim HS, Jacobson KA. Kim HS, et al. Org Lett. 2003 May 15;5(10):1665-8. doi: 10.1021/ol034326z. Org Lett. 2003. PMID: 12735747 Free PMC article.

8

A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.

Choi Y, George C, Comin MJ, Barchi JJ Jr, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. Choi Y, et al. Among authors: kim hs. J Med Chem. 2003 Jul 17;46(15):3292-9. doi: 10.1021/jm030116g. J Med Chem. 2003. PMID: 12852759

9

Pyran Template Approach to the Design of Novel A₃ Adenosine Receptor Antagonists.

Li AH, Ji XD, Kim HS, Melman N, Jacobson KA. Li AH, et al. Among authors: kim hs. Drug Dev Res. 1999 Dec;48(4):171-177. doi: 10.1002/(SICI)1098-2299(199912)48:4<171::AID-DDR4>3.0.CO;2-5. Epub 2000 Feb 11. Drug Dev Res. 1999. PMID: 27182099 Free PMC article.

10

New Synthetic Approach to the Bicyclo[3.1.0]hexane Ring System from (+)-(1R,4R)-4-(Benzyloxymethyl)-4-(hydroxymethyl)cyclopent-2-enol.

Kim SA, Jacobson KA, Kim HS. Kim SA, et al. Among authors: kim hs. Bull Korean Chem Soc. 2005;26(10):1503-1504. doi: 10.5012/bkcs.2005.26.10.1503. Epub 2005 Oct 20. Bull Korean Chem Soc. 2005. PMID: 34824486 Free PMC article. No abstract available.

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