Brown R - Search Results

1

Epigenetic cancer therapies: DNA methyltransferase inhibitors.

Strathdee G, Brown R. Strathdee G, et al. Among authors: brown r. Expert Opin Investig Drugs. 2002 Jun;11(6):747-54. doi: 10.1517/13543784.11.6.747. Expert Opin Investig Drugs. 2002. PMID: 12036419 Review.

2

Epigenomics and epigenetic therapy of cancer.

Brown R, Strathdee G. Brown R, et al. Trends Mol Med. 2002;8(4 Suppl):S43-8. doi: 10.1016/s1471-4914(02)02314-6. Trends Mol Med. 2002. PMID: 11927287 Review.

3

Epigenetic silencing mediated by CpG island methylation: potential as a therapeutic target and as a biomarker.

Teodoridis JM, Strathdee G, Brown R. Teodoridis JM, et al. Among authors: brown r. Drug Resist Updat. 2004 Aug-Oct;7(4-5):267-78. doi: 10.1016/j.drup.2004.06.005. Drug Resist Updat. 2004. PMID: 15533764 Review.

4

Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy.

Strathdee G, Vass JK, Oien KA, Siddiqui N, Curto-Garcia J, Brown R. Strathdee G, et al. Among authors: brown r. Gynecol Oncol. 2005 Jun;97(3):898-903. doi: 10.1016/j.ygyno.2005.03.023. Gynecol Oncol. 2005. PMID: 15894365

5

CpG island methylation of DNA damage response genes in advanced ovarian cancer.

Teodoridis JM, Hall J, Marsh S, Kannall HD, Smyth C, Curto J, Siddiqui N, Gabra H, McLeod HL, Strathdee G, Brown R. Teodoridis JM, et al. Among authors: brown r. Cancer Res. 2005 Oct 1;65(19):8961-7. doi: 10.1158/0008-5472.CAN-05-1187. Cancer Res. 2005. PMID: 16204069

6

Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors.

Appleton K, Mackay HJ, Judson I, Plumb JA, McCormick C, Strathdee G, Lee C, Barrett S, Reade S, Jadayel D, Tang A, Bellenger K, Mackay L, Setanoians A, Schätzlein A, Twelves C, Kaye SB, Brown R. Appleton K, et al. Among authors: brown r. J Clin Oncol. 2007 Oct 10;25(29):4603-9. doi: 10.1200/JCO.2007.10.8688. J Clin Oncol. 2007. PMID: 17925555 Clinical Trial.

7

Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.

Strathdee G, Davies BR, Vass JK, Siddiqui N, Brown R. Strathdee G, et al. Among authors: brown r. Carcinogenesis. 2004 May;25(5):693-701. doi: 10.1093/carcin/bgh066. Epub 2004 Jan 16. Carcinogenesis. 2004. PMID: 14729589

8

Aberrant DNA methylation in cancer: potential clinical interventions.

Strathdee G, Brown R. Strathdee G, et al. Among authors: brown r. Expert Rev Mol Med. 2002 Mar 4;4(4):1-17. doi: 10.1017/S1462399402004222. Expert Rev Mol Med. 2002. PMID: 14987388 Review.

9

CpG-island methylation and epigenetic control of resistance to chemotherapy.

Teodoridis JM, Strathdee G, Plumb JA, Brown R. Teodoridis JM, et al. Among authors: brown r. Biochem Soc Trans. 2004 Dec;32(Pt 6):916-7. doi: 10.1042/BST0320916. Biochem Soc Trans. 2004. PMID: 15506923 Review.

10

Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers.

Wei SH, Chen CM, Strathdee G, Harnsomburana J, Shyu CR, Rahmatpanah F, Shi H, Ng SW, Yan PS, Nephew KP, Brown R, Huang TH. Wei SH, et al. Among authors: brown r. Clin Cancer Res. 2002 Jul;8(7):2246-52. Clin Cancer Res. 2002. PMID: 12114427

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