Giasson BI - Search Results

1

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM. Giasson BI, et al. Neuron. 2002 May 16;34(4):521-33. doi: 10.1016/s0896-6273(02)00682-7. Neuron. 2002. PMID: 12062037 Free article.

2

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

Tu PH, Galvin JE, Baba M, Giasson B, Tomita T, Leight S, Nakajo S, Iwatsubo T, Trojanowski JQ, Lee VM. Tu PH, et al. Ann Neurol. 1998 Sep;44(3):415-22. doi: 10.1002/ana.410440324. Ann Neurol. 1998. PMID: 9749615

3

Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.

Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, Iwatsubo T, Trojanowski JQ. Lippa CF, et al. Am J Pathol. 1998 Nov;153(5):1365-70. doi: 10.1016/s0002-9440(10)65722-7. Am J Pathol. 1998. PMID: 9811326 Free PMC article.

4

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro.

Giasson BI, Uryu K, Trojanowski JQ, Lee VM. Giasson BI, et al. J Biol Chem. 1999 Mar 19;274(12):7619-22. doi: 10.1074/jbc.274.12.7619. J Biol Chem. 1999. PMID: 10075647 Free article.

5

A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease.

Giasson BI, Jakes R, Goedert M, Duda JE, Leight S, Trojanowski JQ, Lee VM. Giasson BI, et al. J Neurosci Res. 2000 Feb 15;59(4):528-33. doi: 10.1002/(SICI)1097-4547(20000215)59:4<528::AID-JNR8>3.0.CO;2-0. J Neurosci Res. 2000. PMID: 10679792

6

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies.

Souza JM, Giasson BI, Chen Q, Lee VM, Ischiropoulos H. Souza JM, et al. Among authors: giasson bi. J Biol Chem. 2000 Jun 16;275(24):18344-9. doi: 10.1074/jbc.M000206200. J Biol Chem. 2000. PMID: 10747881 Free article.

7

Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary.

Bruening W, Giasson BI, Klein-Szanto AJ, Lee VM, Trojanowski JQ, Godwin AK. Bruening W, et al. Among authors: giasson bi. Cancer. 2000 May 1;88(9):2154-63. Cancer. 2000. PMID: 10813729

8

Chaperone-like activity of synucleins.

Souza JM, Giasson BI, Lee VM, Ischiropoulos H. Souza JM, et al. Among authors: giasson bi. FEBS Lett. 2000 May 26;474(1):116-9. doi: 10.1016/s0014-5793(00)01563-5. FEBS Lett. 2000. PMID: 10828462 Free article.

9

Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology.

Galvin JE, Giasson B, Hurtig HI, Lee VM, Trojanowski JQ. Galvin JE, et al. Am J Pathol. 2000 Aug;157(2):361-8. doi: 10.1016/s0002-9440(10)64548-8. Am J Pathol. 2000. PMID: 10934140 Free PMC article.

10

Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy.

Duda JE, Giasson BI, Gur TL, Montine TJ, Robertson D, Biaggioni I, Hurtig HI, Stern MB, Gollomp SM, Grossman M, Lee VM, Trojanowski JQ. Duda JE, et al. Among authors: giasson bi. J Neuropathol Exp Neurol. 2000 Sep;59(9):830-41. doi: 10.1093/jnen/59.9.830. J Neuropathol Exp Neurol. 2000. PMID: 11005264

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