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Page 1
The kinetics of binding to p38MAP kinase by analogues of BIRB 796.
Regan J, Pargellis CA, Cirillo PF, Gilmore T, Hickey ER, Peet GW, Proto A, Swinamer A, Moss N. Regan J, et al. Among authors: gilmore t. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3101-4. doi: 10.1016/s0960-894x(03)00656-5. Bioorg Med Chem Lett. 2003. PMID: 12941343
Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).
Regan J, Capolino A, Cirillo PF, Gilmore T, Graham AG, Hickey E, Kroe RR, Madwed J, Moriak M, Nelson R, Pargellis CA, Swinamer A, Torcellini C, Tsang M, Moss N. Regan J, et al. Among authors: gilmore t. J Med Chem. 2003 Oct 23;46(22):4676-86. doi: 10.1021/jm030121k. J Med Chem. 2003. PMID: 14561087
Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Cirillo PF, Hickey ER, Moss N, Breitfelder S, Betageri R, Fadra T, Gaenzler F, Gilmore T, Goldberg DR, Kamhi V, Kirrane T, Kroe RR, Madwed J, Moriak M, Netherton M, Pargellis CA, Patel UR, Qian KC, Sharma R, Sun S, Swinamer A, Torcellini C, Takahashi H, Tsang M, Xiong Z. Cirillo PF, et al. Among authors: gilmore t. Bioorg Med Chem Lett. 2009 May 1;19(9):2386-91. doi: 10.1016/j.bmcl.2009.03.104. Epub 2009 Mar 26. Bioorg Med Chem Lett. 2009. PMID: 19356929
Quinol-4-ones as steroid A-ring mimetics in nonsteroidal dissociated glucocorticoid agonists.
Regan J, Lee TW, Zindell RM, Bekkali Y, Bentzien J, Gilmore T, Hammach A, Kirrane TM, Kukulka AJ, Kuzmich D, Nelson RM, Proudfoot JR, Ralph M, Pelletier J, Souza D, Zuvela-Jelaska L, Nabozny G, Thomson DS. Regan J, et al. Among authors: gilmore t. J Med Chem. 2006 Dec 28;49(26):7887-96. doi: 10.1021/jm061273t. J Med Chem. 2006. PMID: 17181172
Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores.
Betageri R, Gilmore T, Kuzmich D, Kirrane TM, Bentzien J, Wiedenmayer D, Bekkali Y, Regan J, Berry A, Latli B, Kukulka AJ, Fadra TN, Nelson RM, Goldrick S, Zuvela-Jelaska L, Souza D, Pelletier J, Dinallo R, Panzenbeck M, Torcellini C, Lee H, Pack E, Harcken C, Nabozny G, Thomson DS. Betageri R, et al. Among authors: gilmore t. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6842-51. doi: 10.1016/j.bmcl.2011.09.018. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21963986
Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.
Proudfoot JR, Betageri R, Cardozo M, Gilmore TA, Glynn S, Hickey ER, Jakes S, Kabcenell A, Kirrane TM, Tibolla AK, Lukas S, Patel UR, Sharma R, Yazdanian M, Moss N, Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M. Proudfoot JR, et al. Among authors: gilmore ta. J Med Chem. 2001 Jul 19;44(15):2421-31. doi: 10.1021/jm000446q. J Med Chem. 2001. PMID: 11448224
336 results