Dean N - Search Results

1

Inhibition of spinal protein kinase Calpha expression by an antisense oligonucleotide attenuates morphine infusion-induced tolerance.

Hua XY, Moore A, Malkmus S, Murray SF, Dean N, Yaksh TL, Butler M. Hua XY, et al. Among authors: dean n. Neuroscience. 2002;113(1):99-107. doi: 10.1016/s0306-4522(02)00157-4. Neuroscience. 2002. PMID: 12123688

2

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice.

Butler M, McKay RA, Popoff IJ, Gaarde WA, Witchell D, Murray SF, Dean NM, Bhanot S, Monia BP. Butler M, et al. Diabetes. 2002 Apr;51(4):1028-34. doi: 10.2337/diabetes.51.4.1028. Diabetes. 2002. PMID: 11916922

3

Antisense oligonucleotide inhibition of Bcl-xL and Bid expression in liver regulates responses in a mouse model of Fas-induced fulminant hepatitis.

Zhang H, Taylor J, Luther D, Johnston J, Murray S, Wyatt JR, Watt AT, Koo S, York-DeFalco C, Stecker K, Dean NM. Zhang H, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):24-33. doi: 10.1124/jpet.103.050435. Epub 2003 Jul 31. J Pharmacol Exp Ther. 2003. PMID: 12893848

4

Novel antisense oligonucleotides targeting TGF-beta inhibit in vivo scarring and improve surgical outcome.

Cordeiro MF, Mead A, Ali RR, Alexander RA, Murray S, Chen C, York-Defalco C, Dean NM, Schultz GS, Khaw PT. Cordeiro MF, et al. Among authors: dean nm. Gene Ther. 2003 Jan;10(1):59-71. doi: 10.1038/sj.gt.3301865. Gene Ther. 2003. PMID: 12525838

5

Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression.

Dean N, McKay R, Miraglia L, Howard R, Cooper S, Giddings J, Nicklin P, Meister L, Ziel R, Geiger T, Muller M, Fabbro D. Dean N, et al. Cancer Res. 1996 Aug 1;56(15):3499-507. Cancer Res. 1996. PMID: 8758918

6

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression.

McKay RA, Miraglia LJ, Cummins LL, Owens SR, Sasmor H, Dean NM. McKay RA, et al. Among authors: dean nm. J Biol Chem. 1999 Jan 15;274(3):1715-22. doi: 10.1074/jbc.274.3.1715. J Biol Chem. 1999. PMID: 9880552 Free article.

7

The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells.

Bost F, McKay R, Dean N, Mercola D. Bost F, et al. Among authors: dean n. J Biol Chem. 1997 Dec 26;272(52):33422-9. doi: 10.1074/jbc.272.52.33422. J Biol Chem. 1997. PMID: 9407138 Free article.

8

Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications.

McKay RA, Cummins LL, Graham MJ, Lesnik EA, Owens SR, Winniman M, Dean NM. McKay RA, et al. Among authors: dean nm. Nucleic Acids Res. 1996 Feb 1;24(3):411-7. doi: 10.1093/nar/24.3.411. Nucleic Acids Res. 1996. PMID: 8602351 Free PMC article.

9

Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides.

Dean NM, McKay R. Dean NM, et al. Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11762-6. doi: 10.1073/pnas.91.24.11762. Proc Natl Acad Sci U S A. 1994. PMID: 7972137 Free PMC article.

10

The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells.

Bost F, McKay R, Bost M, Potapova O, Dean NM, Mercola D. Bost F, et al. Among authors: dean nm. Mol Cell Biol. 1999 Mar;19(3):1938-49. doi: 10.1128/MCB.19.3.1938. Mol Cell Biol. 1999. PMID: 10022881 Free PMC article.

We have previously found that epidermal growth factor (EGF) mediates growth through the Jun N-terminal kinase/stress-activated kinase (JNK/SAPK) pathway in A549 human lung carcinoma cells. As observed here, EGF treatment also greatly enhances the tumorigenicity of A549 cel …

We have previously found that epidermal growth factor (EGF) mediates growth through the Jun N-terminal kinase/stress-activated kinase …

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