Sabatini DM - Search Results

1

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Cell. 2002 Jul 26;110(2):163-75. doi: 10.1016/s0092-8674(02)00808-5. Cell. 2002. PMID: 12150925 Free article.

2

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.

Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH. Sabatini DM, et al. Cell. 1994 Jul 15;78(1):35-43. doi: 10.1016/0092-8674(94)90570-3. Cell. 1994. PMID: 7518356

3

High-sensitivity sequencing of large proteins: partial structure of the rapamycin-FKBP12 target.

Erdjument-Bromage H, Lui M, Sabatini DM, Snyder SH, Tempst P. Erdjument-Bromage H, et al. Among authors: sabatini dm. Protein Sci. 1994 Dec;3(12):2435-46. doi: 10.1002/pro.5560031227. Protein Sci. 1994. PMID: 7756997 Free PMC article.

4

FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse.

Hentges KE, Sirry B, Gingeras AC, Sarbassov D, Sonenberg N, Sabatini D, Peterson AS. Hentges KE, et al. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13796-801. doi: 10.1073/pnas.241184198. Epub 2001 Nov 13. Proc Natl Acad Sci U S A. 2001. PMID: 11707573 Free PMC article.

5

Enumeration of the simian virus 40 early region elements necessary for human cell transformation.

Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, DeCaprio JA, Weinberg RA. Hahn WC, et al. Among authors: sabatini dm. Mol Cell Biol. 2002 Apr;22(7):2111-23. doi: 10.1128/MCB.22.7.2111-2123.2002. Mol Cell Biol. 2002. PMID: 11884599 Free PMC article.

6

The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.

Peng T, Golub TR, Sabatini DM. Peng T, et al. Among authors: sabatini dm. Mol Cell Biol. 2002 Aug;22(15):5575-84. doi: 10.1128/MCB.22.15.5575-5584.2002. Mol Cell Biol. 2002. PMID: 12101249 Free PMC article.

7

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.

Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Mol Cell. 2003 Apr;11(4):895-904. doi: 10.1016/s1097-2765(03)00114-x. Mol Cell. 2003. PMID: 12718876 Free article.

8

Raptor and mTOR: subunits of a nutrient-sensitive complex.

Kim DH, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Curr Top Microbiol Immunol. 2004;279:259-70. doi: 10.1007/978-3-642-18930-2_15. Curr Top Microbiol Immunol. 2004. PMID: 14560962 Review.

9

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.

Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. Curr Biol. 2004 Jul 27;14(14):1296-302. doi: 10.1016/j.cub.2004.06.054. Curr Biol. 2004. PMID: 15268862 Free article.

10

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. Science. 2005 Feb 18;307(5712):1098-101. doi: 10.1126/science.1106148. Science. 2005. PMID: 15718470

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