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Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein.
Durley RC, Grapperhaus ML, Hickory BS, Massa MA, Wang JL, Spangler DP, Mischke DA, Parnas BL, Fobian YM, Rath NP, Honda DD, Zeng M, Connolly DT, Heuvelman DM, Witherbee BJ, Melton MA, Glenn KC, Krul ES, Smith ME, Sikorski JA. Durley RC, et al. Among authors: zeng m. J Med Chem. 2002 Aug 29;45(18):3891-904. doi: 10.1021/jm020038h. J Med Chem. 2002. PMID: 12190312
Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein.
Durley RC, Grapperhaus ML, Massa MA, Mischke DA, Parnas BL, Fobian YM, Rath NP, Honda DD, Zeng M, Connolly DT, Heuvelman DM, Witherbee BJ, Glenn KC, Krul ES, Smith ME, Sikorski JA. Durley RC, et al. Among authors: zeng m. J Med Chem. 2000 Nov 30;43(24):4575-8. doi: 10.1021/jm000337b. J Med Chem. 2000. PMID: 11101348 No abstract available.
Small molecule inhibitors of bacterial transcription complex formation.
Wenholz DS, Zeng M, Ma C, Mielczarek M, Yang X, Bhadbhade M, Black DSC, Lewis PJ, Griffith R, Kumar N. Wenholz DS, et al. Among authors: zeng m. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4302-4308. doi: 10.1016/j.bmcl.2017.08.036. Epub 2017 Aug 19. Bioorg Med Chem Lett. 2017. PMID: 28866270
4,183 results