Hotez PJ - Search Results

1

Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity.

Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Williamson AL, et al. Among authors: hotez pj. FASEB J. 2002 Sep;16(11):1458-60. doi: 10.1096/fj.02-0181fje. Epub 2002 Jul 18. FASEB J. 2002. PMID: 12205047

2

Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion.

Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Williamson AL, et al. Among authors: hotez pj. J Infect Dis. 2003 Feb 1;187(3):484-94. doi: 10.1086/367708. Epub 2003 Jan 24. J Infect Dis. 2003. PMID: 12552433

3

Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus.

Ranjit N, Zhan B, Hamilton B, Stenzel D, Lowther J, Pearson M, Gorman J, Hotez P, Loukas A. Ranjit N, et al. J Infect Dis. 2009 Mar 15;199(6):904-12. doi: 10.1086/597048. J Infect Dis. 2009. PMID: 19434933

4

Digestive proteases of blood-feeding nematodes.

Williamson AL, Brindley PJ, Knox DP, Hotez PJ, Loukas A. Williamson AL, et al. Among authors: hotez pj. Trends Parasitol. 2003 Sep;19(9):417-23. doi: 10.1016/s1471-4922(03)00189-2. Trends Parasitol. 2003. PMID: 12957519 Review.

5

A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus.

Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A. Ranjit N, et al. Among authors: hotez pj. Mol Biochem Parasitol. 2008 Aug;160(2):90-9. doi: 10.1016/j.molbiopara.2008.04.008. Epub 2008 Apr 22. Mol Biochem Parasitol. 2008. PMID: 18501979

6

An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection.

Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, Jones K, Keegan B, Hotez PJ, Loukas A. Pearson MS, et al. Among authors: hotez pj. FASEB J. 2009 Sep;23(9):3007-19. doi: 10.1096/fj.09-131433. Epub 2009 Apr 20. FASEB J. 2009. PMID: 19380510 Free PMC article.

7

A pore-forming haemolysin from the hookworm, Ancylostoma caninum.

Don TA, Jones MK, Smyth D, O'Donoghue P, Hotez P, Loukas A. Don TA, et al. Int J Parasitol. 2004 Aug;34(9):1029-35. doi: 10.1016/j.ijpara.2004.04.013. Int J Parasitol. 2004. PMID: 15313129

8

Hookworm vaccines: past, present, and future.

Loukas A, Bethony J, Brooker S, Hotez P. Loukas A, et al. Lancet Infect Dis. 2006 Nov;6(11):733-41. doi: 10.1016/S1473-3099(06)70630-2. Lancet Infect Dis. 2006. PMID: 17067922 Review.

9

Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs.

Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ. Loukas A, et al. Among authors: hotez pj. PLoS Med. 2005 Oct;2(10):e295. doi: 10.1371/journal.pmed.0020295. Epub 2005 Oct 4. PLoS Med. 2005. PMID: 16231975 Free PMC article. Clinical Trial.

10

Hookworm infection.

Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R, Croese J, Bethony JM. Loukas A, et al. Among authors: hotez pj. Nat Rev Dis Primers. 2016 Dec 8;2:16088. doi: 10.1038/nrdp.2016.88. Nat Rev Dis Primers. 2016. PMID: 27929101 Review.

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