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Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease.
Williams AT, Chen J, Coley K, Batini C, Izquierdo A, Packer R, Abner E, Kanoni S, Shepherd DJ, Free RC, Hollox EJ, Brunskill NJ, Ntalla I, Reeve N, Brightling CE, Venn L, Adams E, Bee C, Wallace SE, Pareek M, Hansell AL, Esko T; Estonian Biobank Research Team; Stow D, Jacobs BM, van Heel DA; Genes & Health Research Team; Hennah W, Rao BS, Dudbridge F, Wain LV, Shrine N, Tobin MD, John C. Williams AT, et al. Among authors: van heel da. Nat Commun. 2023 Oct 23;14(1):6713. doi: 10.1038/s41467-023-42284-5. Nat Commun. 2023. PMID: 37872160 Free PMC article.
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.
Zhou W, Kanai M, Wu KH, Rasheed H, Tsuo K, Hirbo JB, Wang Y, Bhattacharya A, Zhao H, Namba S, Surakka I, Wolford BN, Lo Faro V, Lopera-Maya EA, Läll K, Favé MJ, Partanen JJ, Chapman SB, Karjalainen J, Kurki M, Maasha M, Brumpton BM, Chavan S, Chen TT, Daya M, Ding Y, Feng YA, Guare LA, Gignoux CR, Graham SE, Hornsby WE, Ingold N, Ismail SI, Johnson R, Laisk T, Lin K, Lv J, Millwood IY, Moreno-Grau S, Nam K, Palta P, Pandit A, Preuss MH, Saad C, Setia-Verma S, Thorsteinsdottir U, Uzunovic J, Verma A, Zawistowski M, Zhong X, Afifi N, Al-Dabhani KM, Al Thani A, Bradford Y, Campbell A, Crooks K, de Bock GH, Damrauer SM, Douville NJ, Finer S, Fritsche LG, Fthenou E, Gonzalez-Arroyo G, Griffiths CJ, Guo Y, Hunt KA, Ioannidis A, Jansonius NM, Konuma T, Lee MTM, Lopez-Pineda A, Matsuda Y, Marioni RE, Moatamed B, Nava-Aguilar MA, Numakura K, Patil S, Rafaels N, Richmond A, Rojas-Muñoz A, Shortt JA, Straub P, Tao R, Vanderwerff B, Vernekar M, Veturi Y, Barnes KC, Boezen M, Chen Z, Chen CY, Cho J, Smith GD, Finucane HK, Franke L, Gamazon ER, Ganna A, Gaunt TR, Ge T, Huang H, Huffman J, Katsanis N, Koskela JT, Lajonchere C, Law MH, Li L, Lindgren CM, Loos RJF, MacGregor S, Matsuda K, Olsen CM… See abstract for full author list ➔ Zhou W, et al. Among authors: van heel da. Cell Genom. 2022 Oct 12;2(10):100192. doi: 10.1016/j.xgen.2022.100192. eCollection 2022 Oct 12. Cell Genom. 2022. PMID: 36777996 Free PMC article.
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
Patel AP, Wang M, Ruan Y, Koyama S, Clarke SL, Yang X, Tcheandjieu C, Agrawal S, Fahed AC, Ellinor PT; Genes & Health Research Team; the Million Veteran Program; Tsao PS, Sun YV, Cho K, Wilson PWF, Assimes TL, van Heel DA, Butterworth AS, Aragam KG, Natarajan P, Khera AV. Patel AP, et al. Among authors: van heel da. Nat Med. 2023 Jul;29(7):1793-1803. doi: 10.1038/s41591-023-02429-x. Epub 2023 Jul 6. Nat Med. 2023. PMID: 37414900 Free PMC article.
Polygenic prediction of preeclampsia and gestational hypertension.
Honigberg MC, Truong B, Khan RR, Xiao B, Bhatta L, Vy HMT, Guerrero RF, Schuermans A, Selvaraj MS, Patel AP, Koyama S, Cho SMJ, Vellarikkal SK, Trinder M, Urbut SM, Gray KJ, Brumpton BM, Patil S, Zöllner S, Antopia MC, Saxena R, Nadkarni GN, Do R, Yan Q, Pe'er I, Verma SS, Gupta RM, Haas DM, Martin HC, van Heel DA, Laisk T, Natarajan P. Honigberg MC, et al. Among authors: van heel da. Nat Med. 2023 Jun;29(6):1540-1549. doi: 10.1038/s41591-023-02374-9. Epub 2023 May 29. Nat Med. 2023. PMID: 37248299 Free PMC article.
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.
Márquez A, Kerick M, Zhernakova A, Gutierrez-Achury J, Chen WM, Onengut-Gumuscu S, González-Álvaro I, Rodriguez-Rodriguez L, Rios-Fernández R, González-Gay MA; Coeliac Disease Immunochip Consortium; Rheumatoid Arthritis Consortium International for Immunochip (RACI); International Scleroderma Group; Type 1 Diabetes Genetics Consortium; Mayes MD, Raychaudhuri S, Rich SS, Wijmenga C, Martín J. Márquez A, et al. Genome Med. 2018 Dec 20;10(1):97. doi: 10.1186/s13073-018-0604-8. Genome Med. 2018. PMID: 30572963 Free PMC article.
Genetics of inflammatory bowel disease: a reappraisal.
Orchard TR, Satsangi J, Van Heel D, Jewell DP. Orchard TR, et al. Scand J Immunol. 2000 Jan;51(1):10-7. doi: 10.1046/j.1365-3083.2000.00656.x. Scand J Immunol. 2000. PMID: 10632970 Free article. Review.
Inflammatory bowel disease: progress toward a gene.
van Heel DA, Satsangi J, Carey AH, Jewell DP. van Heel DA, et al. Can J Gastroenterol. 2000 Mar;14(3):207-18. doi: 10.1155/2000/361309. Can J Gastroenterol. 2000. PMID: 10758418 Review.
154 results