Wek RC - Search Results

1

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.

Zhang P, McGrath BC, Reinert J, Olsen DS, Lei L, Gill S, Wek SA, Vattem KM, Wek RC, Kimball SR, Jefferson LS, Cavener DR. Zhang P, et al. Among authors: wek sa, wek rc. Mol Cell Biol. 2002 Oct;22(19):6681-8. doi: 10.1128/MCB.22.19.6681-6688.2002. Mol Cell Biol. 2002. PMID: 12215525 Free PMC article.

2

Surviving and Adapting to Stress: Translational Control and the Integrated Stress Response.

Wek RC, Anthony TG, Staschke KA. Wek RC, et al. Antioxid Redox Signal. 2023 Aug;39(4-6):351-373. doi: 10.1089/ars.2022.0123. Epub 2023 May 9. Antioxid Redox Signal. 2023. PMID: 36943285 Free PMC article. Review.

3

An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response.

Amin PH, Carlson KR, Wek RC. Amin PH, et al. Among authors: wek rc. J Biol Chem. 2023 Feb;299(2):102864. doi: 10.1016/j.jbc.2022.102864. Epub 2022 Dec 31. J Biol Chem. 2023. PMID: 36596357 Free PMC article.

4

Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2.

Wek RC, Cannon JF, Dever TE, Hinnebusch AG. Wek RC, et al. Mol Cell Biol. 1992 Dec;12(12):5700-10. doi: 10.1128/mcb.12.12.5700-5710.1992. Mol Cell Biol. 1992. PMID: 1333044 Free PMC article.

5

Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases.

Ramirez M, Wek RC, Vazquez de Aldana CR, Jackson BM, Freeman B, Hinnebusch AG. Ramirez M, et al. Among authors: wek rc. Mol Cell Biol. 1992 Dec;12(12):5801-15. doi: 10.1128/mcb.12.12.5801-5815.1992. Mol Cell Biol. 1992. PMID: 1448107 Free PMC article.

6

The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.

Wek SA, Zhu S, Wek RC. Wek SA, et al. Among authors: wek rc. Mol Cell Biol. 1995 Aug;15(8):4497-506. doi: 10.1128/MCB.15.8.4497. Mol Cell Biol. 1995. PMID: 7623840 Free PMC article.

7

Multicopy tRNA genes functionally suppress mutations in yeast eIF-2 alpha kinase GCN2: evidence for separate pathways coupling GCN4 expression to unchanged tRNA.

Vazquez de Aldana CR, Wek RC, Segundo PS, Truesdell AG, Hinnebusch AG. Vazquez de Aldana CR, et al. Among authors: wek rc. Mol Cell Biol. 1994 Dec;14(12):7920-32. doi: 10.1128/mcb.14.12.7920-7932.1994. Mol Cell Biol. 1994. PMID: 7969132 Free PMC article.

8

Expression of vaccinia virus K3L protein in yeast inhibits eukaryotic initiation factor-2 kinase GCN2 and the general amino acid control pathway.

Qian W, Zhu S, Sobolev AY, Wek RC. Qian W, et al. Among authors: wek rc. J Biol Chem. 1996 May 31;271(22):13202-7. doi: 10.1074/jbc.271.22.13202. J Biol Chem. 1996. PMID: 8662715 Free article.

9

Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2.

Zhu S, Sobolev AY, Wek RC. Zhu S, et al. Among authors: wek rc. J Biol Chem. 1996 Oct 4;271(40):24989-94. doi: 10.1074/jbc.271.40.24989. J Biol Chem. 1996. PMID: 8798780 Free article.

10

Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase.

Olsen DS, Jordan B, Chen D, Wek RC, Cavener DR. Olsen DS, et al. Among authors: wek rc. Genetics. 1998 Jul;149(3):1495-509. doi: 10.1093/genetics/149.3.1495. Genetics. 1998. PMID: 9649537 Free PMC article.

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