Sharpless NE - Search Results

1

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.

Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. Bardeesy N, et al. Among authors: sharpless ne. Nature. 2002 Sep 12;419(6903):162-7. doi: 10.1038/nature01045. Nature. 2002. PMID: 12226664 Free article.

2

The INK4A/ARF locus and its two gene products.

Sharpless NE, DePinho RA. Sharpless NE, et al. Curr Opin Genet Dev. 1999 Feb;9(1):22-30. doi: 10.1016/s0959-437x(99)80004-5. Curr Opin Genet Dev. 1999. PMID: 10072356 Review.

3

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway.

Frank KM, Sharpless NE, Gao Y, Sekiguchi JM, Ferguson DO, Zhu C, Manis JP, Horner J, DePinho RA, Alt FW. Frank KM, et al. Among authors: sharpless ne. Mol Cell. 2000 Jun;5(6):993-1002. doi: 10.1016/s1097-2765(00)80264-6. Mol Cell. 2000. PMID: 10911993 Free article.

4

p19ARF targets certain E2F species for degradation.

Martelli F, Hamilton T, Silver DP, Sharpless NE, Bardeesy N, Rokas M, DePinho RA, Livingston DM, Grossman SR. Martelli F, et al. Among authors: sharpless ne. Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4455-60. doi: 10.1073/pnas.081061398. Epub 2001 Mar 27. Proc Natl Acad Sci U S A. 2001. PMID: 11274364 Free PMC article.

5

The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.

Bardeesy N, Sharpless NE, DePinho RA, Merlino G. Bardeesy N, et al. Among authors: sharpless ne. Semin Cancer Biol. 2001 Jun;11(3):201-18. doi: 10.1006/scbi.2000.0371. Semin Cancer Biol. 2001. PMID: 11407945 Review.

6

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.

Sharpless NE, Bardeesy N, Lee KH, Carrasco D, Castrillon DH, Aguirre AJ, Wu EA, Horner JW, DePinho RA. Sharpless NE, et al. Nature. 2001 Sep 6;413(6851):86-91. doi: 10.1038/35092592. Nature. 2001. PMID: 11544531

7

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.

Sharpless NE, Ferguson DO, O'Hagan RC, Castrillon DH, Lee C, Farazi PA, Alson S, Fleming J, Morton CC, Frank K, Chin L, Alt FW, DePinho RA. Sharpless NE, et al. Mol Cell. 2001 Dec;8(6):1187-96. doi: 10.1016/s1097-2765(01)00425-7. Mol Cell. 2001. PMID: 11779495 Free article.

8

p16(INK4a) and p53 deficiency cooperate in tumorigenesis.

Sharpless NE, Alson S, Chan S, Silver DP, Castrillon DH, DePinho RA. Sharpless NE, et al. Cancer Res. 2002 May 15;62(10):2761-5. Cancer Res. 2002. PMID: 12019151

9

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

Artandi SE, Alson S, Tietze MK, Sharpless NE, Ye S, Greenberg RA, Castrillon DH, Horner JW, Weiler SR, Carrasco RD, DePinho RA. Artandi SE, et al. Among authors: sharpless ne. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8191-6. doi: 10.1073/pnas.112515399. Epub 2002 May 28. Proc Natl Acad Sci U S A. 2002. PMID: 12034875 Free PMC article.

10

Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.

Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Bachoo RM, et al. Among authors: sharpless ne. Cancer Cell. 2002 Apr;1(3):269-77. doi: 10.1016/s1535-6108(02)00046-6. Cancer Cell. 2002. PMID: 12086863 Free article.

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