Sugiura T - Search Results

1

Synthesis and testing of 2alpha-modified 1alpha,25-dihydroxyvitamin D(3) analogues with a double side chain: marked cell differentiation activity.

Suhara Y, Kittaka A, Kishimoto S, Calverley MJ, Fujishima T, Saito N, Sugiura T, Waku K, Takayama H. Suhara Y, et al. Among authors: sugiura t. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3255-8. doi: 10.1016/s0960-894x(02)00722-9. Bioorg Med Chem Lett. 2002. PMID: 12392726

2

Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.

Ono K, Yoshida A, Saito N, Fujishima T, Honzawa S, Suhara Y, Kishimoto S, Sugiura T, Waku K, Takayama H, Kittaka A. Ono K, et al. Among authors: sugiura t. J Org Chem. 2003 Sep 19;68(19):7407-15. doi: 10.1021/jo034787y. J Org Chem. 2003. PMID: 12968893

3

Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3.

Honzawa S, Suhara Y, Nihei K, Saito N, Kishimoto S, Fujishima T, Kurihara M, Sugiura T, Waku K, Takayama H, Kittaka A. Honzawa S, et al. Among authors: sugiura t. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3503-6. doi: 10.1016/s0960-894x(03)00739-x. Bioorg Med Chem Lett. 2003. PMID: 14505658

4

2,2-Functionalized analogues of 1alpha,25-dihydroxyvitamin D3, the potent inducers of cell differentiation.

Fujishima T, Kittaka A, Kurihara M, Saito N, Honzawa S, Kishimoto S, Sugiura T, Waku K, Takayama H. Fujishima T, et al. Among authors: sugiura t. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):89-92. doi: 10.1016/j.jsbmb.2004.03.053. J Steroid Biochem Mol Biol. 2004. PMID: 15225752

5

Synthesis and biological evaluation of several structural analogs of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.

Suhara Y, Oka S, Kittaka A, Takayama H, Waku K, Sugiura T. Suhara Y, et al. Among authors: sugiura t. Bioorg Med Chem. 2007 Jan 15;15(2):854-67. doi: 10.1016/j.bmc.2006.10.049. Epub 2006 Oct 27. Bioorg Med Chem. 2007. PMID: 17110113

6

(2S,2'R)-analogue of LG190178 is a major active isomer.

Hakamata W, Sato Y, Okuda H, Honzawa S, Saito N, Kishimoto S, Yamashita A, Sugiura T, Kittaka A, Kurihara M. Hakamata W, et al. Among authors: sugiura t. Bioorg Med Chem Lett. 2008 Jan 1;18(1):120-3. doi: 10.1016/j.bmcl.2007.11.007. Epub 2007 Nov 5. Bioorg Med Chem Lett. 2008. PMID: 18054230

7

The 2alpha-(3-hydroxypropyl) group as an active motif in vitamin D3 analogues as agonists of the mutant vitamin D receptor (Arg274Leu).

Honzawa S, Yamamoto Y, Yamashita A, Sugiura T, Kurihara M, Arai MA, Kato S, Kittaka A. Honzawa S, et al. Among authors: sugiura t. Bioorg Med Chem. 2008 Mar 15;16(6):3002-24. doi: 10.1016/j.bmc.2007.12.039. Epub 2008 Jan 14. Bioorg Med Chem. 2008. PMID: 18248997

8

Cannabinoid receptors and their endogenous ligands.

Sugiura T, Waku K. Sugiura T, et al. J Biochem. 2002 Jul;132(1):7-12. doi: 10.1093/oxfordjournals.jbchem.a003200. J Biochem. 2002. PMID: 12097154 Free article. Review.

9

2-arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism.

Kishimoto S, Gokoh M, Oka S, Muramatsu M, Kajiwara T, Waku K, Sugiura T. Kishimoto S, et al. Among authors: sugiura t. J Biol Chem. 2003 Jul 4;278(27):24469-75. doi: 10.1074/jbc.M301359200. Epub 2003 Apr 23. J Biol Chem. 2003. PMID: 12711605 Free article.

10

2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells.

Kishimoto S, Kobayashi Y, Oka S, Gokoh M, Waku K, Sugiura T. Kishimoto S, et al. Among authors: sugiura t. J Biochem. 2004 Apr;135(4):517-24. doi: 10.1093/jb/mvh063. J Biochem. 2004. PMID: 15115777 Free article.

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