Suhara Y - Search Results

1

Synthesis and testing of 2alpha-modified 1alpha,25-dihydroxyvitamin D(3) analogues with a double side chain: marked cell differentiation activity.

Suhara Y, Kittaka A, Kishimoto S, Calverley MJ, Fujishima T, Saito N, Sugiura T, Waku K, Takayama H. Suhara Y, et al. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3255-8. doi: 10.1016/s0960-894x(02)00722-9. Bioorg Med Chem Lett. 2002. PMID: 12392726

2

Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds.

Sugiura T, Kodaka T, Nakane S, Miyashita T, Kondo S, Suhara Y, Takayama H, Waku K, Seki C, Baba N, Ishima Y. Sugiura T, et al. Among authors: suhara y. J Biol Chem. 1999 Jan 29;274(5):2794-801. doi: 10.1074/jbc.274.5.2794. J Biol Chem. 1999. PMID: 9915812 Free article.

3

Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells.

Sugiura T, Kondo S, Kishimoto S, Miyashita T, Nakane S, Kodaka T, Suhara Y, Takayama H, Waku K. Sugiura T, et al. Among authors: suhara y. J Biol Chem. 2000 Jan 7;275(1):605-12. doi: 10.1074/jbc.275.1.605. J Biol Chem. 2000. PMID: 10617657 Free article.

4

Syntheses and biological evaluation of novel 2alpha-substituted 1alpha,25-dihydroxyvitamin D3 analogues.

Suhara Y, Nihei KI, Tanigawa H, Fujishima T, Konno K, Nakagawa K, Okano T, Takayama H. Suhara Y, et al. Bioorg Med Chem Lett. 2000 May 15;10(10):1129-32. doi: 10.1016/s0960-894x(00)00189-x. Bioorg Med Chem Lett. 2000. PMID: 10843234

5

Synthesis and biological activities of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, and its metabolically stable ether-linked analogues.

Suhara Y, Takayama H, Nakane S, Miyashita T, Waku K, Sugiura T. Suhara Y, et al. Chem Pharm Bull (Tokyo). 2000 Jul;48(7):903-7. doi: 10.1248/cpb.48.903. Chem Pharm Bull (Tokyo). 2000. PMID: 10923815

6

A concise and efficient route to 2alpha-(omega-hydroxyalkoxy)-1alpha,25-dihydroxyvi tam in D3: remarkably high affinity to vitamin D receptor.

Kittaka A, Suhara Y, Takayanagi H, Fujishima T, Kurihara M, Takayama H. Kittaka A, et al. Among authors: suhara y. Org Lett. 2000 Aug 24;2(17):2619-22. doi: 10.1021/ol006222j. Org Lett. 2000. PMID: 10990411

7

Synthesis and biological activities of novel structural analogues of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.

Suhara Y, Nakane S, Arai S, Takayama H, Waku K, Ishima Y, Sugiura T. Suhara Y, et al. Bioorg Med Chem Lett. 2001 Aug 6;11(15):1985-8. doi: 10.1016/s0960-894x(01)00350-x. Bioorg Med Chem Lett. 2001. PMID: 11454463

8

Efficient and versatile synthesis of novel 2alpha-substituted 1alpha,25-dihydroxyvitamin D(3) analogues and their docking to vitamin D receptors.

Suhara Y, Nihei KI, Kurihara M, Kittaka A, Yamaguchi K, Fujishima T, Konno K, Miyata N, Takayama H. Suhara Y, et al. J Org Chem. 2001 Dec 28;66(26):8760-71. doi: 10.1021/jo010375i. J Org Chem. 2001. PMID: 11749604

9

Design and efficient synthesis of new stable 1alpha,25-dihydroxy-19-norvitamin D3 analogues containing amide bond.

Suhara Y, Kittaka A, Ono K, Kurihara M, Fujishima T, Yoshida A, Takayama H. Suhara Y, et al. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3533-6. doi: 10.1016/s0960-894x(02)00800-4. Bioorg Med Chem Lett. 2002. PMID: 12443770

10

2 alpha-(3-hydroxypropyl)- and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 accessible to vitamin D receptor mutant related to hereditary vitamin D-resistant rickets.

Kittaka A, Kurihara M, Peleg S, Suhara Y, Takayama H. Kittaka A, et al. Among authors: suhara y. Chem Pharm Bull (Tokyo). 2003 Mar;51(3):357-8. doi: 10.1248/cpb.51.357. Chem Pharm Bull (Tokyo). 2003. PMID: 12612432 Free article.

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