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Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induce durable complete chimerism and sustained remissions in patients with hematological diseases.
Niederwieser D, Maris M, Shizuru JA, Petersdorf E, Hegenbart U, Sandmaier BM, Maloney DG, Storer B, Lange T, Chauncey T, Deininger M, Pönisch W, Anasetti C, Woolfrey A, Little MT, Blume KG, McSweeney PA, Storb RF. Niederwieser D, et al. Among authors: little mt. Blood. 2003 Feb 15;101(4):1620-9. doi: 10.1182/blood-2002-05-1340. Epub 2002 Oct 3. Blood. 2003. PMID: 12393457 Free article.
Kinetics of engraftment in patients with hematologic malignancies given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning.
Baron F, Baker JE, Storb R, Gooley TA, Sandmaier BM, Maris MB, Maloney DG, Heimfeld S, Oparin D, Zellmer E, Radich JP, Grumet FC, Blume KG, Chauncey TR, Little MT. Baron F, et al. Among authors: little mt. Blood. 2004 Oct 15;104(8):2254-62. doi: 10.1182/blood-2004-04-1506. Epub 2004 Jun 29. Blood. 2004. PMID: 15226174 Free article.
Engraftment of early erythroid progenitors is not delayed after non-myeloablative major ABO-incompatible haematopoietic stem cell transplantation.
Maciej Zaucha J, Mielcarek M, Takatu A, Little MT, Gooley T, Baker J, Maloney DG, Sandmaier BM, Maris M, Chauncey T, Storb R, Torok-Storb B. Maciej Zaucha J, et al. Among authors: little mt. Br J Haematol. 2002 Dec;119(3):740-50. doi: 10.1046/j.1365-2141.2002.03905.x. Br J Haematol. 2002. PMID: 12437653 Free article.
Postgrafting immunosuppression with sirolimus and cyclosporine facilitates stable mixed hematopoietic chimerism in dogs given sublethal total body irradiation before marrow transplantation from DLA-identical littermates.
Hogan WJ, Little MT, Zellmer E, Friedetzky A, Diaconescu R, Gisburne S, Lee R, Kuhr C, Storb R. Hogan WJ, et al. Among authors: little mt. Biol Blood Marrow Transplant. 2003 Aug;9(8):489-95. doi: 10.1016/s1083-8791(03)00148-4. Biol Blood Marrow Transplant. 2003. PMID: 12931117 Free article.
110 results