Leonard WJ - Search Results

1

Serine phosphorylation of Stat5 proteins in lymphocytes stimulated with IL-2.

Xue HH, Fink DW Jr, Zhang X, Qin J, Turck CW, Leonard WJ. Xue HH, et al. Among authors: leonard wj. Int Immunol. 2002 Nov;14(11):1263-71. doi: 10.1093/intimm/dxf101. Int Immunol. 2002. PMID: 12407017

2

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

Migone TS, Lin JX, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G, Leonard WJ. Migone TS, et al. Among authors: leonard wj. Science. 1995 Jul 7;269(5220):79-81. doi: 10.1126/science.7604283. Science. 1995. PMID: 7604283

3

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.

Lin JX, Mietz J, Modi WS, John S, Leonard WJ. Lin JX, et al. Among authors: leonard wj. J Biol Chem. 1996 May 3;271(18):10738-44. J Biol Chem. 1996. PMID: 8631883 Free article.

4

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation.

Friedmann MC, Migone TS, Russell SM, Leonard WJ. Friedmann MC, et al. Among authors: leonard wj. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2077-82. doi: 10.1073/pnas.93.5.2077. Proc Natl Acad Sci U S A. 1996. PMID: 8700888 Free PMC article.

5

An IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I(Y) and a GATA family protein.

John S, Robbins CM, Leonard WJ. John S, et al. Among authors: leonard wj. EMBO J. 1996 Oct 15;15(20):5627-35. EMBO J. 1996. PMID: 8896456 Free PMC article.

6

Interleukin-2 (IL-2)-mediated induction of the IL-2 receptor alpha chain gene. Critical role of two functionally redundant tyrosine residues in the IL-2 receptor beta chain cytoplasmic domain and suggestion that these residues mediate more than Stat5 activation.

Ascherman DP, Migone TS, Friedmann MC, Leonard WJ. Ascherman DP, et al. Among authors: leonard wj. J Biol Chem. 1997 Mar 28;272(13):8704-9. doi: 10.1074/jbc.272.13.8704. J Biol Chem. 1997. PMID: 9079703 Free article.

7

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction.

Nakajima H, Liu XW, Wynshaw-Boris A, Rosenthal LA, Imada K, Finbloom DS, Hennighausen L, Leonard WJ. Nakajima H, et al. Among authors: leonard wj. Immunity. 1997 Nov;7(5):691-701. doi: 10.1016/s1074-7613(00)80389-1. Immunity. 1997. PMID: 9390692 Free article.

8

Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.

Zhu MH, Berry JA, Russell SM, Leonard WJ. Zhu MH, et al. Among authors: leonard wj. J Biol Chem. 1998 Apr 24;273(17):10719-25. doi: 10.1074/jbc.273.17.10719. J Biol Chem. 1998. PMID: 9553136 Free article.

9

Jaks and STATs: biological implications.

Leonard WJ, O'Shea JJ. Leonard WJ, et al. Annu Rev Immunol. 1998;16:293-322. doi: 10.1146/annurev.immunol.16.1.293. Annu Rev Immunol. 1998. PMID: 9597132 Review.

10

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity.

Imada K, Bloom ET, Nakajima H, Horvath-Arcidiacono JA, Udy GB, Davey HW, Leonard WJ. Imada K, et al. Among authors: leonard wj. J Exp Med. 1998 Dec 7;188(11):2067-74. doi: 10.1084/jem.188.11.2067. J Exp Med. 1998. PMID: 9841920 Free PMC article.

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