Kubodera N - Search Results

1

Two novel metabolic pathways of 22-oxacalcitriol (OCT). C-25 dehydration and C-3 epimerization and biological activities of novel OCT metabolites.

Kamao M, Tatematsu S, Hatakeyama S, Ozono K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: kubodera n. J Biol Chem. 2003 Jan 17;278(3):1463-71. doi: 10.1074/jbc.M203773200. Epub 2002 Nov 1. J Biol Chem. 2003. PMID: 12417596 Free article.

2

C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.

Kamao M, Tatematsu S, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Ozono K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: kubodera n. J Biol Chem. 2004 Apr 16;279(16):15897-907. doi: 10.1074/jbc.M311473200. Epub 2004 Feb 2. J Biol Chem. 2004. PMID: 14757768 Free article.

3

Cell specificity and properties of the C-3 epimerization of Vitamin D3 metabolites.

Kamao M, Tatematsu S, Sawada N, Sakaki T, Hatakeyama S, Kubodera N, Okano T. Kamao M, et al. Among authors: kubodera n. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):39-42. doi: 10.1016/j.jsbmb.2004.03.048. J Steroid Biochem Mol Biol. 2004. PMID: 15225744

4

Measurement and characterization of C-3 epimerization activity toward vitamin D3.

Kamao M, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: kubodera n. Arch Biochem Biophys. 2005 Apr 1;436(1):196-205. doi: 10.1016/j.abb.2005.01.017. Arch Biochem Biophys. 2005. PMID: 15752725

5

Singly dehydroxylated A-ring analogues of 19-nor-1alpha,25-dihydroxyvitamin D3 and 19-nor-22-oxa-1alpha,25-dihydroxyvitamin D3: novel vitamin D3 analogues with potent transcriptional activity but extremely low affinity for vitamin D receptor.

Okano T, Nakagawa K, Tsugawa N, Ozono K, Kubodera N, Osawa A, Terada M, Mikami K. Okano T, et al. Among authors: kubodera n. Biol Pharm Bull. 1998 Dec;21(12):1300-5. doi: 10.1248/bpb.21.1300. Biol Pharm Bull. 1998. PMID: 9881643 Free article.

6

In vitro biological activities of a series of 2 beta-substituted analogues of 1 alpha,25-dihydroxyvitamin D3.

Tsugawa N, Nakagawa K, Kurobe M, Ono Y, Kubodera N, Ozono K, Okano T. Tsugawa N, et al. Among authors: kubodera n. Biol Pharm Bull. 2000 Jan;23(1):66-71. doi: 10.1248/bpb.23.66. Biol Pharm Bull. 2000. PMID: 10706413 Free article.

7

Catalytic asymmetric syntheses and biological activities of singly dehydroxylated 19-nor-1alpha,25-dihydroxyvitamin D(3) A-ring analogs in cancer cell differentiation and apoptosis.

Okano T, Nakagawa K, Kubodera N, Ozono K, Isaka A, Osawa A, Terada M, Mikami K. Okano T, et al. Among authors: kubodera n. Chem Biol. 2000 Mar;7(3):173-84. doi: 10.1016/s1074-5521(00)00087-9. Chem Biol. 2000. PMID: 10712934

8

Synthesis and evaluation of A-ring diastereomers of 1alpha,25-dihydroxy-22-oxavitamin D3 (OCT).

Hatakeyama S, Okano T, Maeyama J, Esumi T, Hiyamizu H, Iwabuchi Y, Nakagawa K, Ozono K, Kawase A, Kubodera N. Hatakeyama S, et al. Among authors: kubodera n. Bioorg Med Chem. 2001 Feb;9(2):403-15. doi: 10.1016/s0968-0896(00)00259-5. Bioorg Med Chem. 2001. PMID: 11249133

9

Isolation, identification and biological activity of 24R,25-dihydroxy-3-epi-vitamin D3: a novel metabolite of 24R,25-dihydroxyvitamin D3 produced in rat osteosarcoma cells (UMR 106).

Kamao M, Tatematsu S, Reddy GS, Hatakeyama S, Sugiura M, Ohashi N, Kubodera N, Okano T. Kamao M, et al. Among authors: kubodera n. J Nutr Sci Vitaminol (Tokyo). 2001 Apr;47(2):108-15. doi: 10.3177/jnsv.47.108. J Nutr Sci Vitaminol (Tokyo). 2001. PMID: 11508700

10

Synthesis of all possible A-ring diastereomers at the 1- and 3-positions of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71) using C2-symmetrical epoxide as a common starting material.

Kubodera N, Hatakeyama S. Kubodera N, et al. Anticancer Res. 2009 Sep;29(9):3571-8. Anticancer Res. 2009. PMID: 19667150 Free article.

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