Bonomo RA - Search Results

1

Amino acid substitutions at Ambler position Gly238 in the SHV-1 beta-lactamase: exploring sequence requirements for resistance to penicillins and cephalosporins.

Hujer AM, Hujer KM, Helfand MS, Anderson VE, Bonomo RA. Hujer AM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2002 Dec;46(12):3971-7. doi: 10.1128/AAC.46.12.3971-3977.2002. Antimicrob Agents Chemother. 2002. PMID: 12435703 Free PMC article.

2

Complementary roles of mutations at positions 69 and 242 in a class A beta-lactamase.

Bonomo RA, Dawes CG, Knox JR, Shlaes DM. Bonomo RA, et al. Biochim Biophys Acta. 1995 Feb 22;1247(1):113-20. doi: 10.1016/0167-4838(94)00187-l. Biochim Biophys Acta. 1995. PMID: 7873579

3

beta-Lactamase mutations far from the active site influence inhibitor binding.

Bonomo RA, Dawes CG, Knox JR, Shlaes DM. Bonomo RA, et al. Biochim Biophys Acta. 1995 Feb 22;1247(1):121-5. doi: 10.1016/0167-4838(94)00188-m. Biochim Biophys Acta. 1995. PMID: 7873581

4

Molecular genetics of resistance to both ceftazidime and beta-lactam-beta-lactamase inhibitor combinations in Klebsiella pneumoniae and in vivo response to beta-lactam therapy.

Rice LB, Carias LL, Bonomo RA, Shlaes DM. Rice LB, et al. Among authors: bonomo ra. J Infect Dis. 1996 Jan;173(1):151-8. doi: 10.1093/infdis/173.1.151. J Infect Dis. 1996. PMID: 8537652

5

OHIO-1 beta-lactamase mutants: Asp179Gly mutation confers resistance to ceftazidime.

Bonomo RA, Rudin SD, Shlaes DM. Bonomo RA, et al. FEMS Microbiol Lett. 1997 Jul 15;152(2):275-8. doi: 10.1111/j.1574-6968.1997.tb10439.x. FEMS Microbiol Lett. 1997. PMID: 9231421

6

Construction and characterization of an OHIO-1 beta-lactamase bearing Met69Ile and Gly238Ser mutations.

Bonomo RA, Knox JR, Rudin SD, Shlaes DM. Bonomo RA, et al. Antimicrob Agents Chemother. 1997 Sep;41(9):1940-3. doi: 10.1128/AAC.41.9.1940. Antimicrob Agents Chemother. 1997. PMID: 9303389 Free PMC article.

7

Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme.

Lin S, Thomas M, Shlaes DM, Rudin SD, Knox JR, Anderson V, Bonomo RA. Lin S, et al. Among authors: bonomo ra. Biochem J. 1998 Jul 15;333 ( Pt 2)(Pt 2):395-400. doi: 10.1042/bj3330395. Biochem J. 1998. PMID: 9735103 Free PMC article.

8

Structure of the SHV-1 beta-lactamase.

Kuzin AP, Nukaga M, Nukaga Y, Hujer AM, Bonomo RA, Knox JR. Kuzin AP, et al. Among authors: bonomo ra. Biochemistry. 1999 May 4;38(18):5720-7. doi: 10.1021/bi990136d. Biochemistry. 1999. PMID: 10231522

9

OHIO-1 beta-lactamase mutants: the Arg244Ser mutant and resistance to beta-lactams and beta-lactamase inhibitors.

Lin S, Thomas M, Mark S, Anderson V, Bonomo RA. Lin S, et al. Among authors: bonomo ra. Biochim Biophys Acta. 1999 Jun 15;1432(1):125-36. doi: 10.1016/s0167-4838(99)00025-4. Biochim Biophys Acta. 1999. PMID: 10366735

10

High-level expression of chromosomally encoded SHV-1 beta-lactamase and an outer membrane protein change confer resistance to ceftazidime and piperacillin-tazobactam in a clinical isolate of Klebsiella pneumoniae.

Rice LB, Carias LL, Hujer AM, Bonafede M, Hutton R, Hoyen C, Bonomo RA. Rice LB, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2000 Feb;44(2):362-7. doi: 10.1128/AAC.44.2.362-367.2000. Antimicrob Agents Chemother. 2000. PMID: 10639363 Free PMC article.

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