Herdewijn P - Search Results

1

Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods.

Manallack DT, Pitt WR, Herdewijn P, Balzarini J, De Clercq E, Sanderson MR, Sohi M, Wien F, Munier-Lehmann H, Haouz A, Delarue M. Manallack DT, et al. Among authors: herdewijn p. J Enzyme Inhib Med Chem. 2002 Jun;17(3):167-74. doi: 10.1080/14756360290032949. J Enzyme Inhib Med Chem. 2002. PMID: 12443042 Free article.

2

Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.

Vanheusden V, Munier-Lehmann H, Pochet S, Herdewijn P, Van Calenbergh S. Vanheusden V, et al. Among authors: herdewijn p. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2695-8. doi: 10.1016/s0960-894x(02)00551-6. Bioorg Med Chem Lett. 2002. PMID: 12217356

3

Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.

Haouz A, Vanheusden V, Munier-Lehmann H, Froeyen M, Herdewijn P, Van Calenbergh S, Delarue M. Haouz A, et al. Among authors: herdewijn p. J Biol Chem. 2003 Feb 14;278(7):4963-71. doi: 10.1074/jbc.M209630200. Epub 2002 Nov 25. J Biol Chem. 2003. PMID: 12454011 Free article.

4

3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.

Vanheusden V, Munier-Lehmann H, Froeyen M, Dugué L, Heyerick A, De Keukeleire D, Pochet S, Busson R, Herdewijn P, Van Calenbergh S. Vanheusden V, et al. Among authors: herdewijn p. J Med Chem. 2003 Aug 28;46(18):3811-21. doi: 10.1021/jm021108n. J Med Chem. 2003. PMID: 12930144 Free article.

5

Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.

Vanheusden V, Van Rompaey P, Munier-Lehmann H, Pochet S, Herdewijn P, Van Calenbergh S. Vanheusden V, et al. Among authors: herdewijn p. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3045-8. doi: 10.1016/s0960-894x(03)00643-7. Bioorg Med Chem Lett. 2003. PMID: 12941330

6

Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.

Vanheusden V, Munier-Lehmann H, Froeyen M, Busson R, Rozenski J, Herdewijn P, Van Calenbergh S. Vanheusden V, et al. Among authors: herdewijn p. J Med Chem. 2004 Dec 2;47(25):6187-94. doi: 10.1021/jm040847w. J Med Chem. 2004. PMID: 15566289

7

5-Substituted pyrimidines with a 1,5-anhydro-2, 3-dideoxy-D-arabino-hexitol moiety at N-1: synthesis, antiviral activity, conformational analysis, and interaction with viral thymidine kinase.

Ostrowski T, Wroblowski B, Busson R, Rozenski J, De Clercq E, Bennett MS, Champness JN, Summers WC, Sanderson MR, Herdewijn P. Ostrowski T, et al. Among authors: herdewijn p. J Med Chem. 1998 Oct 22;41(22):4343-53. doi: 10.1021/jm980287z. J Med Chem. 1998. PMID: 9784109

8

Mechanism of cytostatic action of novel 5-(thien-2-yl)- and 5-(furan-2-yl)-substituted pyrimidine nucleoside analogues against tumor cells transfected by the thymidine kinase gene of herpes simplex virus.

Bohman C, Balzarini J, Wigerinck P, Van Aerschot A, Herdewijn P, De Clercq E. Bohman C, et al. Among authors: herdewijn p. J Biol Chem. 1994 Mar 18;269(11):8036-43. J Biol Chem. 1994. PMID: 8132526 Free article.

9

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.

Champness JN, Bennett MS, Wien F, Visse R, Summers WC, Herdewijn P, de Clerq E, Ostrowski T, Jarvest RL, Sanderson MR. Champness JN, et al. Among authors: herdewijn p. Proteins. 1998 Aug 15;32(3):350-61. doi: 10.1002/(sici)1097-0134(19980815)32:3<350::aid-prot10>3.0.co;2-8. Proteins. 1998. PMID: 9715911

10

Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.

Kögler M, Busson R, De Jonghe S, Rozenski J, Van Belle K, Louat T, Munier-Lehmann H, Herdewijn P. Kögler M, et al. Among authors: herdewijn p. Chem Biodivers. 2012 Mar;9(3):536-56. doi: 10.1002/cbdv.201100285. Chem Biodivers. 2012. PMID: 22422522

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

510 results

Search Page

Filters