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Vacuolar-type H(+)-ATPase inhibitory activity of synthetic analogues of the concanamycins: is the hydrogen bond network involving the lactone carbonyl, the hemiacetal hydroxy group, and the C-19 hydroxy group essential for the biological activity of the concanamycins?
Yoshimoto Y, Jyojima T, Arita T, Ueda M, Imoto M, Matsumura S, Toshima K. Yoshimoto Y, et al. Among authors: toshima k. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3525-8. doi: 10.1016/s0960-894x(02)00806-5. Bioorg Med Chem Lett. 2002. PMID: 12443768
Chemical Synthesis and DNA Photocleavage of the Intercalator-Carbohydrate Hybrid Moiety of the Neocarzinostatin Chromophore This research was partially supported by a Grant-in-Aid for Encouragement of Young Scientists from the Ministry of Education, Science, Sports, and Culture, Japan, and a research grant of Keio University Special Grant-in-Aid for Innovative Collaborative Research Projects.
Toshima K, Takai S, Maeda Y, Takano R, Matsumura S. Toshima K, et al. Angew Chem Int Ed Engl. 2000 Oct 16;39(20):3656-3658. doi: 10.1002/1521-3773(20001016)39:20<3656::aid-anie3656>3.0.co;2-o. Angew Chem Int Ed Engl. 2000. PMID: 11091429 No abstract available.
Total Synthesis of Bafilomycin A(1).
Toshima K, Jyojima T, Yamaguchi H, Noguchi Y, Yoshida T, Murase H, Nakata M, Matsumura S. Toshima K, et al. J Org Chem. 1997 May 16;62(10):3271-3284. doi: 10.1021/jo970314d. J Org Chem. 1997. PMID: 11671714
185 results