Mulder GJ - Search Results

1

Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance.

Burg D, Mulder GJ. Burg D, et al. Among authors: mulder gj. Drug Metab Rev. 2002 Nov;34(4):821-63. doi: 10.1081/dmr-120015695. Drug Metab Rev. 2002. PMID: 12487151 Review.

2

Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling.

Burg D, Riepsaame J, Pont C, Mulder G, van de Water B. Burg D, et al. Biochem Pharmacol. 2006 Jan 12;71(3):268-77. doi: 10.1016/j.bcp.2005.11.003. Epub 2005 Dec 7. Biochem Pharmacol. 2006. PMID: 16337611

3

Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors.

Burg D, Filippov DV, Hermanns R, van der Marel GA, van Boom JH, Mulder GJ. Burg D, et al. Among authors: mulder gj. Bioorg Med Chem. 2002 Jan;10(1):195-205. doi: 10.1016/s0968-0896(01)00269-3. Bioorg Med Chem. 2002. PMID: 11738622

4

Inhibition of glutathione S-transferase in rat hepatocytes by a glycine-tetrazole modified S-alkyl-GSH analogue.

Burg D, Hameetman L, Filippov DV, van der Marel GA, Mulder GJ. Burg D, et al. Among authors: mulder gj. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1579-82. doi: 10.1016/s0960-894x(02)00247-0. Bioorg Med Chem Lett. 2002. PMID: 12039566

5

Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs.

Burg D, Wielinga P, Zelcer N, Saeki T, Mulder GJ, Borst P. Burg D, et al. Among authors: mulder gj. Mol Pharmacol. 2002 Nov;62(5):1160-6. doi: 10.1124/mol.62.5.1160. Mol Pharmacol. 2002. PMID: 12391280

6

In vivo characterization and modulation of the glutathione/glutathione S-transferase system in cancer patients.

Mulders TM, Keizer HJ, Breimer DD, Mulder GJ. Mulders TM, et al. Among authors: mulder gj. Drug Metab Rev. 1995;27(1-2):191-229. doi: 10.3109/03602539509029823. Drug Metab Rev. 1995. PMID: 7641576 Review. No abstract available.

7

Inhibition of glutathione conjugation by glutathione analogues in the perfused rat liver. Effect of esterification on the potency of gamma-L-glutamyl-alpha-(D-2-aminoadipyl)-N-2-heptylamine.

Ouwerkerk-Mahadevan S, Tirona RG, Ripping RA, Ploemen JH, van Bladeren PJ, Pang KS, van Boom JH, Mulder GJ. Ouwerkerk-Mahadevan S, et al. Among authors: mulder gj. Drug Metab Dispos. 1997 Oct;25(10):1137-43. Drug Metab Dispos. 1997. PMID: 9321516

8

Inhibition of glutathione conjugation in the rat in vivo by analogues of glutathione conjugates.

Ouwerkerk-Mahadevan S, Mulder GJ. Ouwerkerk-Mahadevan S, et al. Among authors: mulder gj. Chem Biol Interact. 1998 Apr 24;111-112:163-76. doi: 10.1016/s0009-2797(97)00159-2. Chem Biol Interact. 1998. PMID: 9679552

9

Stereoselectivity of glutathione conjugation in vivo, in the perfused liver and in isolated hepatocytes.

Mulder GJ, te Koppele JM, Schipper CG, Snel WH, Pang KS, Polhuijs M. Mulder GJ, et al. Drug Metab Rev. 1991;23(3-4):311-30. doi: 10.3109/03602539109029762. Drug Metab Rev. 1991. PMID: 1935574 Review. No abstract available.

10

Glutathione analogues as novel inhibitors of rat and human glutathione S-transferase isoenzymes, as well as of glutathione conjugation in isolated rat hepatocytes and in the rat in vivo.

Ouwerkerk-Mahadevan S, van Boom JH, Dreef-Tromp MC, Ploemen JH, Meyer DJ, Mulder GJ. Ouwerkerk-Mahadevan S, et al. Among authors: mulder gj. Biochem J. 1995 May 15;308 ( Pt 1)(Pt 1):283-90. doi: 10.1042/bj3080283. Biochem J. 1995. PMID: 7755575 Free PMC article.

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