Kastelein JJ - Search Results

1

Haplotype analysis of the CETP gene: not TaqIB, but the closely linked -629C-->A polymorphism and a novel promoter variant are independently associated with CETP concentration.

Klerkx AH, Tanck MW, Kastelein JJ, Molhuizen HO, Jukema JW, Zwinderman AH, Kuivenhoven JA. Klerkx AH, et al. Among authors: kastelein jj. Hum Mol Genet. 2003 Jan 15;12(2):111-23. doi: 10.1093/hmg/ddg013. Hum Mol Genet. 2003. PMID: 12499392

2

Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study.

van Dam MJ, de Groot E, Clee SM, Hovingh GK, Roelants R, Brooks-Wilson A, Zwinderman AH, Smit AJ, Smelt AH, Groen AK, Hayden MR, Kastelein JJ. van Dam MJ, et al. Among authors: kastelein jj. Lancet. 2002 Jan 5;359(9300):37-42. doi: 10.1016/S0140-6736(02)07277-X. Lancet. 2002. PMID: 11809185

3

Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study.

de Grooth GJ, Kuivenhoven JA, Stalenhoef AF, de Graaf J, Zwinderman AH, Posma JL, van Tol A, Kastelein JJ. de Grooth GJ, et al. Among authors: kastelein jj. Circulation. 2002 May 7;105(18):2159-65. doi: 10.1161/01.cir.0000015857.31889.7b. Circulation. 2002. PMID: 11994249 Clinical Trial.

4

Frequent mutation in the ABCC6 gene (R1141X) is associated with a strong increase in the prevalence of coronary artery disease.

Trip MD, Smulders YM, Wegman JJ, Hu X, Boer JM, ten Brink JB, Zwinderman AH, Kastelein JJ, Feskens EJ, Bergen AA. Trip MD, et al. Among authors: kastelein jj. Circulation. 2002 Aug 13;106(7):773-5. doi: 10.1161/01.cir.0000028420.27813.c0. Circulation. 2002. PMID: 12176944

5

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

Boekholdt SM, Trip MD, Peters RJ, Engelen M, Boer JM, Feskens EJ, Zwinderman AH, Kastelein JJ, Reitsma PH. Boekholdt SM, et al. Among authors: kastelein jj. Arterioscler Thromb Vasc Biol. 2002 Dec 1;22(12):e24-7. doi: 10.1161/01.atv.0000046235.22451.66. Arterioscler Thromb Vasc Biol. 2002. PMID: 12482844

6

A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies.

Elrayess MA, Webb KE, Flavell DM, Syvänne M, Taskinen MR, Frick MH, Nieminen MS, Kesäniemi YA, Pasternack A, Jukema JW, Kastelein JJ, Zwinderman AH, Humphries SE. Elrayess MA, et al. Among authors: kastelein jj. Atherosclerosis. 2003 May;168(1):131-8. doi: 10.1016/s0021-9150(03)00089-3. Atherosclerosis. 2003. PMID: 12732396

7

Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.

Boekholdt SM, Agema WR, Peters RJ, Zwinderman AH, van der Wall EE, Reitsma PH, Kastelein JJ, Jukema JW; REgression GRowth Evaluation Statin Study Group. Boekholdt SM, et al. Among authors: kastelein jj. Circulation. 2003 May 20;107(19):2416-21. doi: 10.1161/01.CIR.0000068311.40161.28. Epub 2003 May 12. Circulation. 2003. PMID: 12742999 Clinical Trial.

8

Regression of carotid and femoral artery intima-media thickness in familial hypercholesterolemia: treatment with simvastatin.

de Sauvage Nolting PR, de Groot E, Zwinderman AH, Buirma RJ, Trip MD, Kastelein JJ. de Sauvage Nolting PR, et al. Among authors: kastelein jj. Arch Intern Med. 2003 Aug 11-25;163(15):1837-41. doi: 10.1001/archinte.163.15.1837. Arch Intern Med. 2003. PMID: 12912721

9

Molecular variation at the apolipoprotein B gene locus in relation to lipids and cardiovascular disease: a systematic meta-analysis.

Boekholdt SM, Peters RJ, Fountoulaki K, Kastelein JJ, Sijbrands EJ. Boekholdt SM, et al. Among authors: kastelein jj. Hum Genet. 2003 Oct;113(5):417-25. doi: 10.1007/s00439-003-0988-3. Epub 2003 Aug 26. Hum Genet. 2003. PMID: 12942366

10

Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events.

Boekholdt SM, Peters RJ, de Maat MP, Zwinderman AH, van Der Wall EE, Reitsma PH, Jukema JW, Kastelein JJ. Boekholdt SM, et al. Among authors: kastelein jj. Am Heart J. 2004 Jan;147(1):181-6. doi: 10.1016/j.ahj.2003.07.008. Am Heart J. 2004. PMID: 14691438 Clinical Trial.

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