Le Beau MM - Search Results

1

A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657.

Sohal J, Phan VT, Chan PV, Davis EM, Patel B, Kelly LM, Abrams TJ, O'Farrell AM, Gilliland DG, Le Beau MM, Kogan SC. Sohal J, et al. Among authors: le beau mm. Blood. 2003 Apr 15;101(8):3188-97. doi: 10.1182/blood-2002-06-1800. Epub 2002 Dec 19. Blood. 2003. PMID: 12515727 Free article.

2

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia.

Le Beau MM, Davis EM, Patel B, Phan VT, Sohal J, Kogan SC. Le Beau MM, et al. Blood. 2003 Aug 1;102(3):1072-4. doi: 10.1182/blood-2003-01-0155. Epub 2003 Apr 10. Blood. 2003. PMID: 12689927 Free article.

3

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.

Phan VT, Shultz DB, Truong BT, Blake TJ, Brown AL, Gonda TJ, Le Beau MM, Kogan SC. Phan VT, et al. Among authors: le beau mm. Mol Cell Biol. 2003 Jul;23(13):4573-85. doi: 10.1128/MCB.23.13.4573-4585.2003. Mol Cell Biol. 2003. PMID: 12808098 Free PMC article.

4

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.

Le Beau MM, Bitts S, Davis EM, Kogan SC. Le Beau MM, et al. Blood. 2002 Apr 15;99(8):2985-91. doi: 10.1182/blood.v99.8.2985. Blood. 2002. PMID: 11929790 Free article.

5

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.

Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. Le DT, et al. Among authors: le beau mm. Blood. 2004 Jun 1;103(11):4243-50. doi: 10.1182/blood-2003-08-2650. Epub 2004 Feb 24. Blood. 2004. PMID: 14982883 Free article.

6

HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo.

Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D, Kogan SC, Radhakrishnan A, Le Beau MM, Largman C, Lawrence HJ. Fischbach NA, et al. Among authors: le beau mm. Blood. 2005 Feb 15;105(4):1456-66. doi: 10.1182/blood-2004-04-1583. Epub 2004 Nov 2. Blood. 2005. PMID: 15522959 Free article.

7

Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia.

Sternsdorf T, Phan VT, Maunakea ML, Ocampo CB, Sohal J, Silletto A, Galimi F, Le Beau MM, Evans RM, Kogan SC. Sternsdorf T, et al. Among authors: le beau mm. Cancer Cell. 2006 Feb;9(2):81-94. doi: 10.1016/j.ccr.2005.12.030. Cancer Cell. 2006. PMID: 16473276 Free article.

8

Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Moore S, Shigematsu H, Ley TJ, Akashi K, Le Beau MM, Gilliland DG. Chan IT, et al. Among authors: le beau mm. Blood. 2006 Sep 1;108(5):1708-15. doi: 10.1182/blood-2006-04-015040. Epub 2006 May 4. Blood. 2006. PMID: 16675706 Free PMC article.

9

Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders.

Joslin JM, Fernald AA, Tennant TR, Davis EM, Kogan SC, Anastasi J, Crispino JD, Le Beau MM. Joslin JM, et al. Among authors: le beau mm. Blood. 2007 Jul 15;110(2):719-26. doi: 10.1182/blood-2007-01-068809. Epub 2007 Apr 9. Blood. 2007. PMID: 17420284 Free PMC article.

10

Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.

Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K. Wong JC, et al. Among authors: le beau mm. Blood. 2010 Jun 3;115(22):4524-32. doi: 10.1182/blood-2009-07-232504. Epub 2010 Mar 16. Blood. 2010. PMID: 20233966 Free PMC article.

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