Metcalf D - Search Results

1

Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis.

Cornish AL, Davey GM, Metcalf D, Purton JF, Corbin JE, Greenhalgh CJ, Darwiche R, Wu L, Nicola NA, Godfrey DI, Heath WR, Hilton DJ, Alexander WS, Starr R. Cornish AL, et al. Among authors: metcalf d. J Immunol. 2003 Jan 15;170(2):878-86. doi: 10.4049/jimmunol.170.2.878. J Immunol. 2003. PMID: 12517953

2

Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).

Metcalf D, Mifsud S, Di Rago L, Nicola NA, Hilton DJ, Alexander WS. Metcalf D, et al. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):943-8. doi: 10.1073/pnas.022628499. Epub 2002 Jan 8. Proc Natl Acad Sci U S A. 2002. PMID: 11782537 Free PMC article.

3

Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b).

Greenhalgh CJ, Bertolino P, Asa SL, Metcalf D, Corbin JE, Adams TE, Davey HW, Nicola NA, Hilton DJ, Alexander WS. Greenhalgh CJ, et al. Among authors: metcalf d. Mol Endocrinol. 2002 Jun;16(6):1394-406. doi: 10.1210/mend.16.6.0845. Mol Endocrinol. 2002. PMID: 12040024

4

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

Greenhalgh CJ, Metcalf D, Thaus AL, Corbin JE, Uren R, Morgan PO, Fabri LJ, Zhang JG, Martin HM, Willson TA, Billestrup N, Nicola NA, Baca M, Alexander WS, Hilton DJ. Greenhalgh CJ, et al. Among authors: metcalf d. J Biol Chem. 2002 Oct 25;277(43):40181-4. doi: 10.1074/jbc.C200450200. Epub 2002 Sep 2. J Biol Chem. 2002. PMID: 12208853 Free article.

5

Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.

Eyles JL, Metcalf D, Grusby MJ, Hilton DJ, Starr R. Eyles JL, et al. Among authors: metcalf d. J Biol Chem. 2002 Nov 15;277(46):43735-40. doi: 10.1074/jbc.M208586200. Epub 2002 Sep 8. J Biol Chem. 2002. PMID: 12221108 Free article.

6

SOCS3 negatively regulates IL-6 signaling in vivo.

Croker BA, Krebs DL, Zhang JG, Wormald S, Willson TA, Stanley EG, Robb L, Greenhalgh CJ, Förster I, Clausen BE, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS. Croker BA, et al. Among authors: metcalf d. Nat Immunol. 2003 Jun;4(6):540-5. doi: 10.1038/ni931. Epub 2003 May 18. Nat Immunol. 2003. PMID: 12754505

7

SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function.

Brender C, Columbus R, Metcalf D, Handman E, Starr R, Huntington N, Tarlinton D, Ødum N, Nicholson SE, Nicola NA, Hilton DJ, Alexander WS. Brender C, et al. Among authors: metcalf d. Mol Cell Biol. 2004 Jul;24(13):6094-103. doi: 10.1128/MCB.24.13.6094-6103.2004. Mol Cell Biol. 2004. PMID: 15199163 Free PMC article.

8

Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling.

Nicholson SE, Metcalf D, Sprigg NS, Columbus R, Walker F, Silva A, Cary D, Willson TA, Zhang JG, Hilton DJ, Alexander WS, Nicola NA. Nicholson SE, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2328-33. doi: 10.1073/pnas.0409675102. Epub 2005 Feb 3. Proc Natl Acad Sci U S A. 2005. PMID: 15695332 Free PMC article.

9

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity.

Fenner JE, Starr R, Cornish AL, Zhang JG, Metcalf D, Schreiber RD, Sheehan K, Hilton DJ, Alexander WS, Hertzog PJ. Fenner JE, et al. Among authors: metcalf d. Nat Immunol. 2006 Jan;7(1):33-9. doi: 10.1038/ni1287. Epub 2005 Nov 27. Nat Immunol. 2006. PMID: 16311601

10

The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo.

Boyle K, Egan P, Rakar S, Willson TA, Wicks IP, Metcalf D, Hilton DJ, Nicola NA, Alexander WS, Roberts AW, Robb L. Boyle K, et al. Among authors: metcalf d. Blood. 2007 Sep 1;110(5):1466-74. doi: 10.1182/blood-2007-03-079178. Epub 2007 May 17. Blood. 2007. PMID: 17510322 Free PMC article.

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