Shimaoka M - Search Results

1

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation.

Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, Jun CD, McCormack A, Zhang R, Joachimiak A, Takagi J, Wang JH, Springer TA. Shimaoka M, et al. Cell. 2003 Jan 10;112(1):99-111. doi: 10.1016/s0092-8674(02)01257-6. Cell. 2003. PMID: 12526797 Free PMC article.

2

Conformational regulation of integrin structure and function.

Shimaoka M, Takagi J, Springer TA. Shimaoka M, et al. Annu Rev Biophys Biomol Struct. 2002;31:485-516. doi: 10.1146/annurev.biophys.31.101101.140922. Epub 2001 Oct 25. Annu Rev Biophys Biomol Struct. 2002. PMID: 11988479 Review.

3

Stabilizing the integrin alpha M inserted domain in alternative conformations with a range of engineered disulfide bonds.

Shimaoka M, Lu C, Salas A, Xiao T, Takagi J, Springer TA. Shimaoka M, et al. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16737-41. doi: 10.1073/pnas.252633099. Epub 2002 Dec 4. Proc Natl Acad Sci U S A. 2002. PMID: 12466503 Free PMC article.

4

Structure and allosteric regulation of the alpha X beta 2 integrin I domain.

Vorup-Jensen T, Ostermeier C, Shimaoka M, Hommel U, Springer TA. Vorup-Jensen T, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1873-8. doi: 10.1073/pnas.0237387100. Epub 2003 Jan 28. Proc Natl Acad Sci U S A. 2003. PMID: 12554829 Free PMC article.

5

Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions.

Yang W, Shimaoka M, Chen J, Springer TA. Yang W, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2333-8. doi: 10.1073/pnas.0307291101. Proc Natl Acad Sci U S A. 2004. PMID: 14983010 Free PMC article.

6

The binding sites for competitive antagonistic, allosteric antagonistic, and agonistic antibodies to the I domain of integrin LFA-1.

Lu C, Shimaoka M, Salas A, Springer TA. Lu C, et al. Among authors: shimaoka m. J Immunol. 2004 Sep 15;173(6):3972-8. doi: 10.4049/jimmunol.173.6.3972. J Immunol. 2004. PMID: 15356146

7

An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.

Song G, Yang Y, Liu JH, Casasnovas JM, Shimaoka M, Springer TA, Wang JH. Song G, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3366-71. doi: 10.1073/pnas.0500200102. Epub 2005 Feb 22. Proc Natl Acad Sci U S A. 2005. PMID: 15728350 Free PMC article.

8

Rational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesion.

Song G, Lazar GA, Kortemme T, Shimaoka M, Desjarlais JR, Baker D, Springer TA. Song G, et al. Among authors: shimaoka m. J Biol Chem. 2006 Feb 24;281(8):5042-9. doi: 10.1074/jbc.M510454200. Epub 2005 Dec 14. J Biol Chem. 2006. PMID: 16354667 Free PMC article.

9

Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1.

Zhang H, Liu JH, Yang W, Springer T, Shimaoka M, Wang JH. Zhang H, et al. Among authors: shimaoka m. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18345-50. doi: 10.1073/pnas.0909301106. Epub 2009 Sep 23. Proc Natl Acad Sci U S A. 2009. PMID: 19805116 Free PMC article.

10

Computational design of an integrin I domain stabilized in the open high affinity conformation.

Shimaoka M, Shifman JM, Jing H, Takagi J, Mayo SL, Springer TA. Shimaoka M, et al. Nat Struct Biol. 2000 Aug;7(8):674-8. doi: 10.1038/77978. Nat Struct Biol. 2000. PMID: 10932253

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