Takagi J - Search Results

1

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation.

Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, Jun CD, McCormack A, Zhang R, Joachimiak A, Takagi J, Wang JH, Springer TA. Shimaoka M, et al. Among authors: takagi j. Cell. 2003 Jan 10;112(1):99-111. doi: 10.1016/s0092-8674(02)01257-6. Cell. 2003. PMID: 12526797 Free PMC article.

2

Stabilizing the integrin alpha M inserted domain in alternative conformations with a range of engineered disulfide bonds.

Shimaoka M, Lu C, Salas A, Xiao T, Takagi J, Springer TA. Shimaoka M, et al. Among authors: takagi j. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16737-41. doi: 10.1073/pnas.252633099. Epub 2002 Dec 4. Proc Natl Acad Sci U S A. 2002. PMID: 12466503 Free PMC article.

3

High affinity ligand binding by integrins does not involve head separation.

Luo BH, Springer TA, Takagi J. Luo BH, et al. Among authors: takagi j. J Biol Chem. 2003 May 9;278(19):17185-9. doi: 10.1074/jbc.M301516200. Epub 2003 Feb 24. J Biol Chem. 2003. PMID: 12600996 Free article.

4

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand.

Luo BH, Springer TA, Takagi J. Luo BH, et al. Among authors: takagi j. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2403-8. doi: 10.1073/pnas.0438060100. Epub 2003 Feb 25. Proc Natl Acad Sci U S A. 2003. PMID: 12604783 Free PMC article.

5

Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface.

Takagi J, Yang Y, Liu JH, Wang JH, Springer TA. Takagi J, et al. Nature. 2003 Aug 21;424(6951):969-74. doi: 10.1038/nature01873. Nature. 2003. PMID: 12931195

6

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides.

Luo BH, Takagi J, Springer TA. Luo BH, et al. Among authors: takagi j. J Biol Chem. 2004 Mar 12;279(11):10215-21. doi: 10.1074/jbc.M312732200. Epub 2003 Dec 16. J Biol Chem. 2004. PMID: 14681220 Free article.

7

A specific interface between integrin transmembrane helices and affinity for ligand.

Luo BH, Springer TA, Takagi J. Luo BH, et al. Among authors: takagi j. PLoS Biol. 2004 Jun;2(6):e153. doi: 10.1371/journal.pbio.0020153. Epub 2004 Jun 15. PLoS Biol. 2004. PMID: 15208712 Free PMC article.

8

Conformational regulation of integrin structure and function.

Shimaoka M, Takagi J, Springer TA. Shimaoka M, et al. Among authors: takagi j. Annu Rev Biophys Biomol Struct. 2002;31:485-516. doi: 10.1146/annurev.biophys.31.101101.140922. Epub 2001 Oct 25. Annu Rev Biophys Biomol Struct. 2002. PMID: 11988479 Review.

9

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling.

Takagi J, Petre BM, Walz T, Springer TA. Takagi J, et al. Cell. 2002 Sep 6;110(5):599-11. doi: 10.1016/s0092-8674(02)00935-2. Cell. 2002. PMID: 12230977 Free article.

10

Integrin activation and structural rearrangement.

Takagi J, Springer TA. Takagi J, et al. Immunol Rev. 2002 Aug;186:141-63. doi: 10.1034/j.1600-065x.2002.18613.x. Immunol Rev. 2002. PMID: 12234369 Review.

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