Kruit WH - Search Results

1

Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses.

Portielje JE, Lamers CH, Kruit WH, Sparreboom A, Bolhuis RL, Stoter G, Huber C, Gratama JW. Portielje JE, et al. Among authors: kruit wh. Clin Cancer Res. 2003 Jan;9(1):76-83. Clin Cancer Res. 2003. PMID: 12538454 Clinical Trial.

2

IL-12: a promising adjuvant for cancer vaccination.

Portielje JE, Gratama JW, van Ojik HH, Stoter G, Kruit WH. Portielje JE, et al. Among authors: kruit wh. Cancer Immunol Immunother. 2003 Mar;52(3):133-44. doi: 10.1007/s00262-002-0356-5. Epub 2003 Feb 12. Cancer Immunol Immunother. 2003. PMID: 12649742 Free PMC article. Review.

3

Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant.

Portielje JE, Kruit WH, Eerenberg AJ, Schuler M, Sparreboom A, Lamers CH, Gratama JW, Stoter G, Huber C, Hack CE. Portielje JE, et al. Among authors: kruit wh. Cancer Immunol Immunother. 2005 Jan;54(1):37-43. doi: 10.1007/s00262-004-0574-0. Cancer Immunol Immunother. 2005. PMID: 15693137 Free PMC article.

4

Dose efficacy study of two schedules of high-dose bolus administration of interleukin 2 and interferon alpha in metastatic melanoma.

Kruit WH, Punt CJ, Goey SH, de Mulder PH, Gratama JW, Eggermont AM, Bolhuis RL, Stoter G. Kruit WH, et al. Br J Cancer. 1996 Sep;74(6):951-5. doi: 10.1038/bjc.1996.463. Br J Cancer. 1996. PMID: 8826864 Free PMC article.

5

High-dose regimen of interleukin-2 and interferon-alpha in combination with lymphokine-activated killer cells in patients with metastatic renal cell cancer.

Kruit WH, Goey SH, Lamers CH, Gratama JW, Visser B, Schmitz PI, Eggermont AM, Bolhuis RL, Stoter G. Kruit WH, et al. J Immunother. 1997 Jul;20(4):312-20. doi: 10.1097/00002371-199707000-00008. J Immunother. 1997. PMID: 9220321 Clinical Trial.

6

Phase I study of subcutaneously administered recombinant human interleukin 12 in patients with advanced renal cell cancer.

Portielje JE, Kruit WH, Schuler M, Beck J, Lamers CH, Stoter G, Huber C, de Boer-Dennert M, Rakhit A, Bolhuis RL, Aulitzky WE. Portielje JE, et al. Among authors: kruit wh. Clin Cancer Res. 1999 Dec;5(12):3983-9. Clin Cancer Res. 1999. PMID: 10632329 Clinical Trial.

7

Interleukin 12 induces activation of fibrinolysis and coagulation in humans.

Portielje JE, Kruit WH, Eerenberg AJ, Schuler M, Sparreboom A, Lamers CH, Bolhuis RL, Stoter G, Huber C, Hack C. Portielje JE, et al. Among authors: kruit wh. Br J Haematol. 2001 Feb;112(2):499-505. doi: 10.1046/j.1365-2141.2001.02592.x. Br J Haematol. 2001. PMID: 11167854 Free article. Clinical Trial.

8

Adoptive immuno-gene therapy of cancer with single chain antibody [scFv(Ig)] gene modified T lymphocytes.

Lamers CH, Sleijfer S, Willemsen RA, Debets R, Kruit WH, Gratama JW, Stoter G. Lamers CH, et al. Among authors: kruit wh. J Biol Regul Homeost Agents. 2004 Apr-Jun;18(2):134-40. J Biol Regul Homeost Agents. 2004. PMID: 15471217 Review.

9

Final report of a phase II study of interleukin 2 and interferon alpha in patients with metastatic melanoma.

Kruit WH, Goey SH, Calabresi F, Lindemann A, Stahel RA, Poliwoda H, Osterwalder B, Stoter G. Kruit WH, et al. Br J Cancer. 1995 Jun;71(6):1319-21. doi: 10.1038/bjc.1995.256. Br J Cancer. 1995. PMID: 7779731 Free PMC article. Clinical Trial.

10

Cardiotoxicity as a dose-limiting factor in a schedule of high dose bolus therapy with interleukin-2 and alpha-interferon. An unexpectedly frequent complication.

Kruit WH, Punt KJ, Goey SH, de Mulder PH, van Hoogenhuyze DC, Henzen-Logmans SC, Stoter G. Kruit WH, et al. Cancer. 1994 Nov 15;74(10):2850-6. doi: 10.1002/1097-0142(19941115)74:10<2850::aid-cncr2820741018>3.0.co;2-t. Cancer. 1994. PMID: 7954247

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