Venkatachalam TK - Search Results

1

Inhibition of mast cell leukotriene release by thiourea derivatives.

Venkatachalam TK, Qazi S, Samuel P, Uckun FM. Venkatachalam TK, et al. Bioorg Med Chem Lett. 2003 Feb 10;13(3):485-8. doi: 10.1016/s0960-894x(02)00992-7. Bioorg Med Chem Lett. 2003. PMID: 12565956

2

Structural requirements for potent anti-human immunodeficiency virus (HIV) and sperm-immobilizing activities of cyclohexenyl thiourea and urea non-nucleoside inhibitors of HIV-1 reverse transcriptase.

D'Cruz OJ, Venkatachalam TK, Mao C, Qazi S, Uckun FM. D'Cruz OJ, et al. Among authors: venkatachalam tk. Biol Reprod. 2002 Dec;67(6):1959-74. doi: 10.1095/biolreprod.102.006478. Biol Reprod. 2002. PMID: 12444075

3

Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reserve transcriptase.

Vig R, Mao C, Venkatachalam TK, Tuel-Ahlgren L, Sudbeck EA, Uckun FM. Vig R, et al. Among authors: venkatachalam tk. Bioorg Med Chem. 1998 Oct;6(10):1789-97. doi: 10.1016/s0968-0896(98)00108-4. Bioorg Med Chem. 1998. PMID: 9839009

4

Structure-based design of N-[2-(1-piperidinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Mao C, Vig R, Venkatachalam TK, Sudbeck EA, Uckun FM. Mao C, et al. Among authors: venkatachalam tk. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2213-8. doi: 10.1016/s0960-894x(98)00384-9. Bioorg Med Chem Lett. 1998. PMID: 9873515

5

Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives.

Venkatachalam TK, Tai HL, Vig R, Chen CL, Jan ST, Uckun FM. Venkatachalam TK, et al. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3121-6. doi: 10.1016/s0960-894x(98)00547-2. Bioorg Med Chem Lett. 1998. PMID: 9873688

6

Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.

Mao C, Sudbeck EA, Venkatachalam TK, Uckun FM. Mao C, et al. Among authors: venkatachalam tk. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1593-8. doi: 10.1016/s0960-894x(99)00235-8. Bioorg Med Chem Lett. 1999. PMID: 10386942

7

N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.

Uckun FM, Mao C, Pendergrass S, Maher D, Zhu D, Tuel-Ahlgren L, Venkatachalam TK. Uckun FM, et al. Among authors: venkatachalam tk. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2721-6. doi: 10.1016/s0960-894x(99)00460-6. Bioorg Med Chem Lett. 1999. PMID: 10509923

8

N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.

Uckun FM, Pendergrass S, Maher D, Zhu D, Tuel-Ahlgren L, Mao C, Venkatachalam TK. Uckun FM, et al. Among authors: venkatachalam tk. Bioorg Med Chem Lett. 1999 Dec 20;9(24):3411-6. doi: 10.1016/s0960-894x(99)00624-1. Bioorg Med Chem Lett. 1999. PMID: 10617082

9

Antioxidant function of phenethyl-5-bromo-pyridyl thiourea compounds with potent anti-HIV activity.

Dong Y, Venkatachalam TK, Narla RK, Trieu VN, Sudbeck EA, Uckun FM. Dong Y, et al. Among authors: venkatachalam tk. Bioorg Med Chem Lett. 2000 Jan 3;10(1):87-90. doi: 10.1016/s0960-894x(99)00581-8. Bioorg Med Chem Lett. 2000. PMID: 10636251

10

Stereochemistry of halopyridyl and thiazolyl thiourea compounds is a major determinant of their potency as nonnucleoside inhibitors of HIV-1 reverse transcriptase.

Venkatachalam TK, Sudbeck EA, Mao C, Uckun FM. Venkatachalam TK, et al. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2071-4. doi: 10.1016/s0960-894x(00)00398-x. Bioorg Med Chem Lett. 2000. PMID: 10999473

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