Ly DH - Search Results

1

Embryonic stem cells: a perfect marriage between gene regulation and regenerative medicine.

Zhou P, Ly DH. Zhou P, et al. Among authors: ly dh. Curr Top Med Chem. 2003;3(6):725-37. doi: 10.2174/1568026033452357. Curr Top Med Chem. 2003. PMID: 12570861 Review.

2

Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA).

Zhou P, Wang M, Du L, Fisher GW, Waggoner A, Ly DH. Zhou P, et al. Among authors: ly dh. J Am Chem Soc. 2003 Jun 11;125(23):6878-9. doi: 10.1021/ja029665m. J Am Chem Soc. 2003. PMID: 12783535

3

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.

Dragulescu-Andrasi A, Zhou P, He G, Ly DH. Dragulescu-Andrasi A, et al. Among authors: ly dh. Chem Commun (Camb). 2005 Jan 14;(2):244-6. doi: 10.1039/b412522c. Epub 2004 Dec 2. Chem Commun (Camb). 2005. PMID: 15724200

4

Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties.

Zhou P, Dragulescu-Andrasi A, Bhattacharya B, O'Keefe H, Vatta P, Hyldig-Nielsen JJ, Ly DH. Zhou P, et al. Among authors: ly dh. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4931-5. doi: 10.1016/j.bmcl.2006.06.052. Epub 2006 Jun 30. Bioorg Med Chem Lett. 2006. PMID: 16809033

5

Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs).

Sahu B, Chenna V, Lathrop KL, Thomas SM, Zon G, Livak KJ, Ly DH. Sahu B, et al. Among authors: ly dh. J Org Chem. 2009 Feb 20;74(4):1509-16. doi: 10.1021/jo802211n. J Org Chem. 2009. PMID: 19161276 Free PMC article.

6

Synthesis of ( R)- and ( S)-Fmoc-Protected Diethylene Glycol Gamma PNA Monomers with High Optical Purity.

Hsieh WC, Shaikh AY, Perera JDR, Thadke SA, Ly DH. Hsieh WC, et al. Among authors: ly dh. J Org Chem. 2019 Feb 1;84(3):1276-1287. doi: 10.1021/acs.joc.8b02714. Epub 2019 Jan 22. J Org Chem. 2019. PMID: 30608165 Free PMC article.

7

Bifunctional small molecule-oligonucleotide hybrid as microRNA inhibitor.

Bhattarai U, Hsieh WC, Yan H, Guo ZF, Shaikh AY, Soltani A, Song Y, Ly DH, Liang FS. Bhattarai U, et al. Among authors: ly dh. Bioorg Med Chem. 2020 Apr 1;28(7):115394. doi: 10.1016/j.bmc.2020.115394. Epub 2020 Feb 18. Bioorg Med Chem. 2020. PMID: 32139203 Free PMC article.

8

Peptide nucleic acid-DNA duplexes: long range hole migration from an internally linked anthraquinone.

Armitage B, Ly D, Koch T, Frydenlund H, Orum H, Batz HG, Schuster GB. Armitage B, et al. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12320-5. doi: 10.1073/pnas.94.23.12320. Proc Natl Acad Sci U S A. 1997. PMID: 9356447 Free PMC article.

9

Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects.

Dragulescu-Andrasi A, Rapireddy S, He G, Bhattacharya B, Hyldig-Nielsen JJ, Zon G, Ly DH. Dragulescu-Andrasi A, et al. Among authors: ly dh. J Am Chem Soc. 2006 Dec 20;128(50):16104-12. doi: 10.1021/ja063383v. J Am Chem Soc. 2006. PMID: 17165763

10

Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity.

Lusvarghi S, Murphy CT, Roy S, Tanious FA, Sacui I, Wilson WD, Ly DH, Armitage BA. Lusvarghi S, et al. Among authors: ly dh. J Am Chem Soc. 2009 Dec 30;131(51):18415-24. doi: 10.1021/ja907250j. J Am Chem Soc. 2009. PMID: 19947597 Free PMC article.

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