Lahusen T - Search Results

1

Flavopiridol-related proinflammatory syndrome is associated with induction of interleukin-6.

Messmann RA, Ullmann CD, Lahusen T, Kalehua A, Wasfy J, Melillo G, Ding I, Headlee D, Figg WD, Sausville EA, Senderowicz AM. Messmann RA, et al. Among authors: lahusen t. Clin Cancer Res. 2003 Feb;9(2):562-70. Clin Cancer Res. 2003. PMID: 12576419 Clinical Trial.

2

Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.

Patel V, Lahusen T, Sy T, Sausville EA, Gutkind JS, Senderowicz AM. Patel V, et al. Among authors: lahusen t. Cancer Res. 2002 Mar 1;62(5):1401-9. Cancer Res. 2002. PMID: 11888912

3

Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).

Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM. Patel V, et al. Among authors: lahusen t. Clin Cancer Res. 2002 Nov;8(11):3549-60. Clin Cancer Res. 2002. PMID: 12429646

4

Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases.

Zaharevitz DW, Gussio R, Leost M, Senderowicz AM, Lahusen T, Kunick C, Meijer L, Sausville EA. Zaharevitz DW, et al. Among authors: lahusen t. Cancer Res. 1999 Jun 1;59(11):2566-9. Cancer Res. 1999. PMID: 10363974

5

Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol.

Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz AM. Carlson B, et al. Among authors: lahusen t. Cancer Res. 1999 Sep 15;59(18):4634-41. Cancer Res. 1999. PMID: 10493518

6

Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes.

Melillo G, Sausville EA, Cloud K, Lahusen T, Varesio L, Senderowicz AM. Melillo G, et al. Among authors: lahusen t. Cancer Res. 1999 Nov 1;59(21):5433-7. Cancer Res. 1999. PMID: 10554012

7

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

Robey RW, Medina-Pérez WY, Nishiyama K, Lahusen T, Miyake K, Litman T, Senderowicz AM, Ross DD, Bates SE. Robey RW, et al. Among authors: lahusen t. Clin Cancer Res. 2001 Jan;7(1):145-52. Clin Cancer Res. 2001. PMID: 11205902

8

Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms.

Sausville EA, Arbuck SG, Messmann R, Headlee D, Bauer KS, Lush RM, Murgo A, Figg WD, Lahusen T, Jaken S, Jing X, Roberge M, Fuse E, Kuwabara T, Senderowicz AM. Sausville EA, et al. Among authors: lahusen t. J Clin Oncol. 2001 Apr 15;19(8):2319-33. doi: 10.1200/JCO.2001.19.8.2319. J Clin Oncol. 2001. PMID: 11304786 Clinical Trial.

9

Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential.

Lahusen T, De Siervi A, Kunick C, Senderowicz AM. Lahusen T, et al. Mol Carcinog. 2003 Apr;36(4):183-94. doi: 10.1002/mc.10114. Mol Carcinog. 2003. PMID: 12669310

10

Assays for cyclin-dependent kinase inhibitors.

Senderowicz AM, Lahusen T. Senderowicz AM, et al. Among authors: lahusen t. Methods Mol Med. 2003;85:39-48. doi: 10.1385/1-59259-380-1:39. Methods Mol Med. 2003. PMID: 12710195 Review. No abstract available.

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