Holland EC - Search Results

1

p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.

Wolf RM, Draghi N, Liang X, Dai C, Uhrbom L, Eklöf C, Westermark B, Holland EC, Resh MD. Wolf RM, et al. Among authors: holland ec. Genes Dev. 2003 Feb 15;17(4):476-87. doi: 10.1101/gad.1040003. Genes Dev. 2003. PMID: 12600941 Free PMC article.

2

Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes.

Holland EC, Hively WP, Gallo V, Varmus HE. Holland EC, et al. Genes Dev. 1998 Dec 1;12(23):3644-9. doi: 10.1101/gad.12.23.3644. Genes Dev. 1998. PMID: 9851971 Free PMC article.

3

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice.

Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN. Holland EC, et al. Nat Genet. 2000 May;25(1):55-7. doi: 10.1038/75596. Nat Genet. 2000. PMID: 10802656

4

Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo.

Holland EC, Li Y, Celestino J, Dai C, Schaefer L, Sawaya RA, Fuller GN. Holland EC, et al. Am J Pathol. 2000 Sep;157(3):1031-7. doi: 10.1016/S0002-9440(10)64615-9. Am J Pathol. 2000. PMID: 10980141 Free PMC article.

5

Animal models of cell cycle dysregulation and the pathogenesis of gliomas.

Holland EC. Holland EC. J Neurooncol. 2001 Feb;51(3):265-76. doi: 10.1023/a:1010609114564. J Neurooncol. 2001. PMID: 11407597 Review.

6

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo.

Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. Dai C, et al. Among authors: holland ec. Genes Dev. 2001 Aug 1;15(15):1913-25. doi: 10.1101/gad.903001. Genes Dev. 2001. PMID: 11485986 Free PMC article.

7

Glioma models.

Dai C, Holland EC. Dai C, et al. Among authors: holland ec. Biochim Biophys Acta. 2001 Aug 31;1551(1):M19-27. doi: 10.1016/s0304-419x(01)00027-0. Biochim Biophys Acta. 2001. PMID: 11553418 Review.

8

Modeling gliomagenesis with somatic cell gene transfer using retroviral vectors.

Uhrbom L, Holland EC. Uhrbom L, et al. Among authors: holland ec. J Neurooncol. 2001 Jul;53(3):297-305. doi: 10.1023/a:1012208314436. J Neurooncol. 2001. PMID: 11718262 Review.

9

MYC expression promotes the proliferation of neural progenitor cells in culture and in vivo.

Fults D, Pedone C, Dai C, Holland EC. Fults D, et al. Among authors: holland ec. Neoplasia. 2002 Jan-Feb;4(1):32-9. doi: 10.1038/sj.neo.7900200. Neoplasia. 2002. PMID: 11922389 Free PMC article.

10

Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.

Uhrbom L, Dai C, Celestino JC, Rosenblum MK, Fuller GN, Holland EC. Uhrbom L, et al. Among authors: holland ec. Cancer Res. 2002 Oct 1;62(19):5551-8. Cancer Res. 2002. PMID: 12359767

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