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Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.
Kitteringham NR, Abdullah A, Walsh J, Randle L, Jenkins RE, Sison R, Goldring CE, Powell H, Sanderson C, Williams S, Higgins L, Yamamoto M, Hayes J, Park BK. Kitteringham NR, et al. Among authors: park bk. J Proteomics. 2010 Jun 16;73(8):1612-31. doi: 10.1016/j.jprot.2010.03.018. Epub 2010 Apr 24. J Proteomics. 2010. PMID: 20399915 Free PMC article.
Identification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: biochemical, pharmacological and toxicological implications.
Walsh J, Jenkins RE, Wong M, Olayanju A, Powell H, Copple I, O'Neill PM, Goldring CE, Kitteringham NR, Park BK. Walsh J, et al. Among authors: park bk. J Proteomics. 2014 Aug 28;108(100):171-87. doi: 10.1016/j.jprot.2014.05.007. Epub 2014 May 21. J Proteomics. 2014. PMID: 24859727 Free PMC article.
Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice.
Goldring CE, Kitteringham NR, Elsby R, Randle LE, Clement YN, Williams DP, McMahon M, Hayes JD, Itoh K, Yamamoto M, Park BK. Goldring CE, et al. Among authors: park bk. Hepatology. 2004 May;39(5):1267-76. doi: 10.1002/hep.20183. Hepatology. 2004. PMID: 15122755
The role of metabolic activation in drug-induced hepatotoxicity.
Park BK, Kitteringham NR, Maggs JL, Pirmohamed M, Williams DP. Park BK, et al. Annu Rev Pharmacol Toxicol. 2005;45:177-202. doi: 10.1146/annurev.pharmtox.45.120403.100058. Annu Rev Pharmacol Toxicol. 2005. PMID: 15822174 Review.
Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes.
Goldring CE, Kitteringham NR, Jenkins R, Lovatt CA, Randle LE, Abdullah A, Owen A, Liu X, Butler PJ, Williams DP, Metcalfe P, Berens C, Hillen W, Foster B, Simpson A, McLellan L, Park BK. Goldring CE, et al. Among authors: park bk. Am J Physiol Cell Physiol. 2006 Jan;290(1):C104-15. doi: 10.1152/ajpcell.00133.2005. Epub 2005 Aug 31. Am J Physiol Cell Physiol. 2006. PMID: 16135546 Free article.
1,552 results