Hasty P - Search Results

1

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

Donoho G, Brenneman MA, Cui TX, Donoviel D, Vogel H, Goodwin EH, Chen DJ, Hasty P. Donoho G, et al. Among authors: hasty p. Genes Chromosomes Cancer. 2003 Apr;36(4):317-31. doi: 10.1002/gcc.10148. Genes Chromosomes Cancer. 2003. PMID: 12619154

2

Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to gamma-radiation and premature senescence.

Morimatsu M, Donoho G, Hasty P. Morimatsu M, et al. Among authors: hasty p. Cancer Res. 1998 Aug 1;58(15):3441-7. Cancer Res. 1998. PMID: 9699678

3

High-throughput inducible expression of transgenes at the Hprt gene in mouse embryonic stem cells.

Donoho G, Hasty P. Donoho G, et al. Among authors: hasty p. Biotechniques. 2003 Mar;34(3):462-4, 466, 468. doi: 10.2144/03343bm02. Biotechniques. 2003. PMID: 12661151 Free article. No abstract available.

4

Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs.

Holcomb VB, Vogel H, Hasty P. Holcomb VB, et al. Among authors: hasty p. Mech Ageing Dev. 2007 Nov-Dec;128(11-12):601-8. doi: 10.1016/j.mad.2007.08.006. Epub 2007 Sep 12. Mech Ageing Dev. 2007. PMID: 17928034 Free PMC article.

5

Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response.

Holcomb VB, Rodier F, Choi Y, Busuttil RA, Vogel H, Vijg J, Campisi J, Hasty P. Holcomb VB, et al. Among authors: hasty p. Cancer Res. 2008 Nov 15;68(22):9497-502. doi: 10.1158/0008-5472.CAN-08-2085. Cancer Res. 2008. PMID: 19010925 Free PMC article.

6

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer.

Li H, Vogel H, Holcomb VB, Gu Y, Hasty P. Li H, et al. Among authors: hasty p. Mol Cell Biol. 2007 Dec;27(23):8205-14. doi: 10.1128/MCB.00785-07. Epub 2007 Sep 17. Mol Cell Biol. 2007. PMID: 17875923 Free PMC article.

7

Unlike p53, p27 failed to exhibit an anti-tumor genetic interaction with Ku80.

Holcomb VB, Vogel H, Hasty P. Holcomb VB, et al. Among authors: hasty p. Cell Cycle. 2009 Aug;8(15):2463-6. doi: 10.4161/cc.8.15.9249. Epub 2009 Aug 11. Cell Cycle. 2009. PMID: 19597334

8

Analysis of ku80-mutant mice and cells with deficient levels of p53.

Lim DS, Vogel H, Willerford DM, Sands AT, Platt KA, Hasty P. Lim DS, et al. Among authors: hasty p. Mol Cell Biol. 2000 Jun;20(11):3772-80. doi: 10.1128/MCB.20.11.3772-3780.2000. Mol Cell Biol. 2000. PMID: 10805721 Free PMC article.

9

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.

Li H, Choi YJ, Hanes MA, Marple T, Vogel H, Hasty P. Li H, et al. Among authors: hasty p. Oncogene. 2009 Apr 23;28(16):1875-8. doi: 10.1038/onc.2009.57. Epub 2009 Mar 30. Oncogene. 2009. PMID: 19330025

10

Fidelity of targeted recombination in human fibroblasts and murine embryonic stem cells.

Zheng H, Hasty P, Brenneman MA, Grompe M, Gibbs RA, Wilson JH, Bradley A. Zheng H, et al. Among authors: hasty p. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8067-71. doi: 10.1073/pnas.88.18.8067. Proc Natl Acad Sci U S A. 1991. PMID: 1896453 Free PMC article.

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