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Circular dichroism and fluorescence of a tyrosine side-chain residue monitors the concentration-dependent equilibrium between U-shaped and coiled-coil conformations of a peptide derived from the catalytic core of HIV-1 integrase.
Porumb H, Zargarian L, Merad H, Maroun R, Mauffret O, Troalen F, Fermandjian S. Porumb H, et al. Among authors: fermandjian s. Biochim Biophys Acta. 2004 Jun 1;1699(1-2):77-86. doi: 10.1016/j.bbapap.2004.01.005. Biochim Biophys Acta. 2004. PMID: 15158714
A synthetic peptide from the human immunodeficiency virus type-1 integrase exhibits coiled-coil properties and interferes with the in vitro integration activity of the enzyme. Correlated biochemical and spectroscopic results.
Sourgen F, Maroun RG, Frère V, Bouziane M, Auclair C, Troalen F, Fermandjian S. Sourgen F, et al. Among authors: fermandjian s. Eur J Biochem. 1996 Sep 15;240(3):765-73. doi: 10.1111/j.1432-1033.1996.0765h.x. Eur J Biochem. 1996. PMID: 8856082 Free article.
Conformational aspects of HIV-1 integrase inhibition by a peptide derived from the enzyme central domain and by antibodies raised against this peptide.
Maroun RG, Krebs D, Roshani M, Porumb H, Auclair C, Troalen F, Fermandjian S. Maroun RG, et al. Among authors: fermandjian s. Eur J Biochem. 1999 Feb;260(1):145-55. doi: 10.1046/j.1432-1327.1999.00130.x. Eur J Biochem. 1999. PMID: 10091594 Free article.
While the activity of antibodies is restricted to recognition of the sole epitope portion, that of the antigenic K159 likely requires interactions of the peptide with the whole 147-175 segment in the protein [Sourgen F., Maroun, R.G., Frere, V., Bouziane, A., Auclair, C., Troalen …
While the activity of antibodies is restricted to recognition of the sole epitope portion, that of the antigenic K159 likely requires intera …
Self-association and domains of interactions of an amphipathic helix peptide inhibitor of HIV-1 integrase assessed by analytical ultracentrifugation and NMR experiments in trifluoroethanol/H(2)O mixtures.
Maroun RG, Krebs D, El Antri S, Deroussent A, Lescot E, Troalen F, Porumb H, Goldberg ME, Fermandjian S. Maroun RG, et al. Among authors: fermandjian s. J Biol Chem. 1999 Nov 26;274(48):34174-85. doi: 10.1074/jbc.274.48.34174. J Biol Chem. 1999. PMID: 10567389 Free article.
123 results