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Strategy to discriminate between high and low affinity bindings of human immunodeficiency virus, type 1 integrase to viral DNA.
J Biol Chem. 2003 May 30;278(22):19966-73. doi: 10.1074/jbc.M211711200. Epub 2003 Mar 7.
J Biol Chem. 2003.
PMID: 12626494
Free article.
Circular dichroism and fluorescence of a tyrosine side-chain residue monitors the concentration-dependent equilibrium between U-shaped and coiled-coil conformations of a peptide derived from the catalytic core of HIV-1 integrase.
Porumb H, Zargarian L, Merad H, Maroun R, Mauffret O, Troalen F, Fermandjian S.
Porumb H, et al. Among authors: merad h.
Biochim Biophys Acta. 2004 Jun 1;1699(1-2):77-86. doi: 10.1016/j.bbapap.2004.01.005.
Biochim Biophys Acta. 2004.
PMID: 15158714
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An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.
Merad H, Porumb H, Zargarian L, René B, Hobaika Z, Maroun RG, Mauffret O, Fermandjian S.
Merad H, et al.
PLoS One. 2009;4(1):e4081. doi: 10.1371/journal.pone.0004081. Epub 2009 Jan 1.
PLoS One. 2009.
PMID: 19119323
Free PMC article.
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Peptide inhibitors of HIV-1 integrase dissociate the enzyme oligomers.
Maroun RG, Gayet S, Benleulmi MS, Porumb H, Zargarian L, Merad H, Leh H, Mouscadet JF, Troalen F, Fermandjian S.
Maroun RG, et al. Among authors: merad h.
Biochemistry. 2001 Nov 20;40(46):13840-8. doi: 10.1021/bi011328n.
Biochemistry. 2001.
PMID: 11705373
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