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Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux.
Kockx M, Rye KA, Gaus K, Quinn CM, Wright J, Sloane T, Sviridov D, Fu Y, Sullivan D, Burnett JR, Rust S, Assmann G, Anantharamaiah GM, Palgunachari MN, Katz SL, Phillips MC, Dean RT, Jessup W, Kritharides L. Kockx M, et al. J Biol Chem. 2004 Jun 18;279(25):25966-77. doi: 10.1074/jbc.M401177200. Epub 2004 Apr 1. J Biol Chem. 2004. PMID: 15066991 Free article.
ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I.
Gelissen IC, Harris M, Rye KA, Quinn C, Brown AJ, Kockx M, Cartland S, Packianathan M, Kritharides L, Jessup W. Gelissen IC, et al. Among authors: kockx m. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):534-40. doi: 10.1161/01.ATV.0000200082.58536.e1. Epub 2005 Dec 15. Arterioscler Thromb Vasc Biol. 2006. PMID: 16357317
Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway.
Kockx M, Guo DL, Traini M, Gaus K, Kay J, Wimmer-Kleikamp S, Rentero C, Burnett JR, Le Goff W, Van Eck M, Stow JL, Jessup W, Kritharides L. Kockx M, et al. J Biol Chem. 2009 Sep 4;284(36):24144-54. doi: 10.1074/jbc.M109.032615. Epub 2009 Jul 9. J Biol Chem. 2009. PMID: 19589783 Free PMC article.
Apolipoprotein E (apoE) is an important regulator of lipid metabolism and atherosclerosis, the secretion of which from human macrophages is regulated by the serine/threonine protein kinase A (PKA) and intracellular calcium (Ca(2+)) (Kockx, M., Guo, D. L., Huby, T., …
Apolipoprotein E (apoE) is an important regulator of lipid metabolism and atherosclerosis, the secretion of which from human macrophages is …
251 results