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Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect.
Tortora G, Caputo R, Damiano V, Melisi D, Bianco R, Fontanini G, Veneziani BM, De Placido S, Bianco AR, Ciardiello F. Tortora G, et al. Among authors: bianco ar, bianco r. Clin Cancer Res. 2003 Apr;9(4):1566-72. Clin Cancer Res. 2003. PMID: 12684433
ZD1839 (Iressa): preclinical studies and pharmacology.
Ciardiello F, Tortora G, De Placido S, Bianco AR. Ciardiello F, et al. Among authors: bianco ar. Tumori. 2002 Jan-Feb;88(1 Suppl 1):S155-7. doi: 10.1177/030089160208800145. Tumori. 2002. PMID: 11989913 No abstract available.
Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase.
Ciardiello F, Caputo R, Damiano V, Caputo R, Troiani T, Vitagliano D, Carlomagno F, Veneziani BM, Fontanini G, Bianco AR, Tortora G. Ciardiello F, et al. Among authors: bianco ar. Clin Cancer Res. 2003 Apr;9(4):1546-56. Clin Cancer Res. 2003. PMID: 12684431
Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.
Ciardiello F, Bianco R, Caputo R, Caputo R, Damiano V, Troiani T, Melisi D, De Vita F, De Placido S, Bianco AR, Tortora G. Ciardiello F, et al. Among authors: bianco ar, bianco r. Clin Cancer Res. 2004 Jan 15;10(2):784-93. doi: 10.1158/1078-0432.ccr-1100-03. Clin Cancer Res. 2004. PMID: 14760102
206 results