Purohit A - Search Results

1

Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.

Fischer DS, Chander SK, Woo LW, Fenton JC, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: purohit a. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):343-9. doi: 10.1016/s0960-0760(03)00048-7. J Steroid Biochem Mol Biol. 2003. PMID: 12711021

2

Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies.

Howarth NM, Purohit A, Robinson JJ, Vicker N, Reed MJ, Potter BV. Howarth NM, et al. Among authors: purohit a. Biochemistry. 2002 Dec 17;41(50):14801-14. doi: 10.1021/bi020543g. Biochemistry. 2002. PMID: 12475228

3

D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase.

Fischer DS, Woo LW, Mahon MF, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: purohit a. Bioorg Med Chem. 2003 Apr 17;11(8):1685-700. doi: 10.1016/s0968-0896(03)00042-7. Bioorg Med Chem. 2003. PMID: 12659755

4

Development of a sensitive high-performance liquid chromatography method for the detection of 667 COUMATE in vivo.

Ireson CR, Parish D, Purohit A, Woo LW, Potter BV, Chander SK, Reed MJ. Ireson CR, et al. Among authors: purohit a. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):337-42. doi: 10.1016/s0960-0760(03)00047-5. J Steroid Biochem Mol Biol. 2003. PMID: 12711020

5

Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate.

Raobaikady B, Purohit A, Chander SK, Woo LW, Leese MP, Potter BV, Reed MJ. Raobaikady B, et al. Among authors: purohit a. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):351-8. doi: 10.1016/s0960-0760(03)00049-9. J Steroid Biochem Mol Biol. 2003. PMID: 12711022

6

First dual aromatase-steroid sulfatase inhibitors.

Woo LW, Sutcliffe OB, Bubert C, Grasso A, Chander SK, Purohit A, Reed MJ, Potter BV. Woo LW, et al. Among authors: purohit a. J Med Chem. 2003 Jul 17;46(15):3193-6. doi: 10.1021/jm034033b. J Med Chem. 2003. PMID: 12852749

7

2-difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitor.

Reed JE, Woo LW, Robinson JJ, Leblond B, Leese MP, Purohit A, Reed MJ, Potter BV. Reed JE, et al. Among authors: purohit a. Biochem Biophys Res Commun. 2004 Apr 23;317(1):169-75. doi: 10.1016/j.bbrc.2004.03.023. Biochem Biophys Res Commun. 2004. PMID: 15047163

8

Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase.

Hejaz HA, Woo LW, Purohit A, Reed MJ, Potter BV. Hejaz HA, et al. Among authors: purohit a. Bioorg Med Chem. 2004 May 15;12(10):2759-72. doi: 10.1016/j.bmc.2004.02.040. Bioorg Med Chem. 2004. PMID: 15110857

9

Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors.

Lawrence HR, Vicker N, Allan GM, Smith A, Mahon MF, Tutill HJ, Purohit A, Reed MJ, Potter BV. Lawrence HR, et al. Among authors: purohit a. J Med Chem. 2005 Apr 21;48(8):2759-62. doi: 10.1021/jm049045r. J Med Chem. 2005. PMID: 15828812

10

A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity.

Wood PM, Woo LW, Humphreys A, Chander SK, Purohit A, Reed MJ, Potter BV. Wood PM, et al. Among authors: purohit a. J Steroid Biochem Mol Biol. 2005 Feb;94(1-3):123-30. doi: 10.1016/j.jsbmb.2004.12.028. Epub 2005 Feb 5. J Steroid Biochem Mol Biol. 2005. PMID: 15862957

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