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Mutations in dynein link motor neuron degeneration to defects in retrograde transport.
Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, Hrabe de Angelis M, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE, Fisher EM. Hafezparast M, et al. Among authors: wabnitz p. Science. 2003 May 2;300(5620):808-12. doi: 10.1126/science.1083129. Science. 2003. PMID: 12730604
Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry.
Yu P, Constien R, Dear N, Katan M, Hanke P, Bunney TD, Kunder S, Quintanilla-Martinez L, Huffstadt U, Schröder A, Jones NP, Peters T, Fuchs H, de Angelis MH, Nehls M, Grosse J, Wabnitz P, Meyer TP, Yasuda K, Schiemann M, Schneider-Fresenius C, Jagla W, Russ A, Popp A, Josephs M, Marquardt A, Laufs J, Schmittwolf C, Wagner H, Pfeffer K, Mudde GC. Yu P, et al. Among authors: wabnitz p. Immunity. 2005 Apr;22(4):451-65. doi: 10.1016/j.immuni.2005.01.018. Immunity. 2005. PMID: 15845450 Free article.
First-in-human study of a pharmacological duodenal exclusion therapy shows reduced postprandial glucose and insulin and increased bile acid and gut hormone concentrations.
Fineman MS, Bryant CLN, Colbert K, Jozefiak TH, Petersen JS, Horowitz M, Vora J, Rayner CK, Wabnitz P, Nimgaonkar A. Fineman MS, et al. Among authors: wabnitz p. Diabetes Obes Metab. 2023 Sep;25(9):2447-2456. doi: 10.1111/dom.15066. Epub 2023 Jun 28. Diabetes Obes Metab. 2023. PMID: 37380614 Clinical Trial.
33 results