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The differential ability of HLA B*5701+ long-term nonprogressors and progressors to restrict human immunodeficiency virus replication is not caused by loss of recognition of autologous viral gag sequences.
Migueles SA, Laborico AC, Imamichi H, Shupert WL, Royce C, McLaughlin M, Ehler L, Metcalf J, Liu S, Hallahan CW, Connors M. Migueles SA, et al. Among authors: shupert wl. J Virol. 2003 Jun;77(12):6889-98. doi: 10.1128/jvi.77.12.6889-6898.2003. J Virol. 2003. PMID: 12768008 Free PMC article.
Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2.
Iyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, Sekaly RP, Kwok WW, Migueles SA, Laborico AC, Shupert WL, Hallahan CW, Davey RT Jr, Dybul M, Vogel S, Metcalf J, Connors M. Iyasere C, et al. Among authors: shupert wl. J Virol. 2003 Oct;77(20):10900-9. doi: 10.1128/jvi.77.20.10900-10909.2003. J Virol. 2003. PMID: 14512540 Free PMC article.
Resistance to replication of human immunodeficiency virus challenge in SCID-Hu mice engrafted with peripheral blood mononuclear cells of nonprogressors is mediated by CD8(+) T cells and associated with a proliferative response to p24 antigen.
de Quiros JC, Shupert WL, McNeil AC, Gea-Banacloche JC, Flanigan M, Savage A, Martino L, Weiskopf EE, Imamichi H, Zhang YM, Adelsburger J, Stevens R, Murphy PM, Zimmerman PA, Hallahan CW, Davey RT Jr, Connors M. de Quiros JC, et al. Among authors: shupert wl. J Virol. 2000 Feb;74(4):2023-8. doi: 10.1128/jvi.74.4.2023-2028.2000. J Virol. 2000. PMID: 10644376 Free PMC article.
HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.
Migueles SA, Sabbaghian MS, Shupert WL, Bettinotti MP, Marincola FM, Martino L, Hallahan CW, Selig SM, Schwartz D, Sullivan J, Connors M. Migueles SA, et al. Among authors: shupert wl. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2709-14. doi: 10.1073/pnas.050567397. Proc Natl Acad Sci U S A. 2000. PMID: 10694578 Free PMC article.
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.
Martin MP, Qi Y, Gao X, Yamada E, Martin JN, Pereyra F, Colombo S, Brown EE, Shupert WL, Phair J, Goedert JJ, Buchbinder S, Kirk GD, Telenti A, Connors M, O'Brien SJ, Walker BD, Parham P, Deeks SG, McVicar DW, Carrington M. Martin MP, et al. Among authors: shupert wl. Nat Genet. 2007 Jun;39(6):733-40. doi: 10.1038/ng2035. Epub 2007 May 13. Nat Genet. 2007. PMID: 17496894 Free PMC article.
Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques.
Hasenkrug KJ, Feldmann F, Myers L, Santiago ML, Guo K, Barrett BS, Mickens KL, Carmody A, Okumura A, Rao D, Collins MM, Messer RJ, Lovaglio J, Shaia C, Rosenke R, van Doremalen N, Clancy C, Saturday G, Hanley P, Smith BJ, Meade-White K, Shupert WL, Hawman DW, Feldmann H. Hasenkrug KJ, et al. Among authors: shupert wl. mBio. 2021 Aug 31;12(4):e0150321. doi: 10.1128/mBio.01503-21. Epub 2021 Jul 27. mBio. 2021. PMID: 34311582 Free PMC article.
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